PXD004993 is an
original dataset announced via ProteomeXchange.
Dataset Summary
Title | Equine OA model - An inflammatory equine model demonstrates dynamic changes of immune response and cartilage matrix molecule degradation in vitro |
Description | Articular cartilage explants were incubated with or without interleukin-1β for 25 days. Media samples collected at 3-day intervals were analysed by quantitative proteomics. Semi-tryptic COMP peptides containing novel neo-epitopes were identified and quantified in cell culture media from cartilage explants. |
HostingRepository | PRIDE |
AnnounceDate | 2024-10-22 |
AnnouncementXML | Submission_2024-10-22_04:09:11.201.xml |
DigitalObjectIdentifier | |
ReviewLevel | Peer-reviewed dataset |
DatasetOrigin | Original dataset |
RepositorySupport | Unsupported dataset by repository |
PrimarySubmitter | Ulla Rüetschi |
SpeciesList | scientific name: Equus caballus (Horse); NCBI TaxID: 9796; |
ModificationList | iodoacetamide derivatized residue |
Instrument | LTQ Orbitrap |
Dataset History
Revision | Datetime | Status | ChangeLog Entry |
0 | 2016-09-19 02:48:11 | ID requested | |
1 | 2018-01-05 01:29:54 | announced | |
⏵ 2 | 2024-10-22 04:09:27 | announced | 2024-10-22: Updated project metadata. |
Publication List
10.3109/03008207.2015.1027340; |
Svala E, L, ö, fgren M, Sihlbom C, R, ü, etschi U, Lindahl A, Ekman S, Ski, ö, ldebrand E, An inflammatory equine model demonstrates dynamic changes of immune response and cartilage matrix molecule degradation in vitro. Connect Tissue Res, 56(4):315-25(2015) [pubmed] |
10.1111/evj.12666; |
Ski, ö, ldebrand E, Ekman S, Mattsson Hult, é, n L, Svala E, Bj, ö, rkman K, Lindahl A, Lundqvist A, Ö, nnerfjord P, Sihlbom C, R, ü, etschi U, Cartilage oligomeric matrix protein neoepitope in the synovial fluid of horses with acute lameness: A new biomarker for the early stages of osteoarthritis. Equine Vet J, 49(5):662-667(2017) [pubmed] |
Keyword List
curator keyword: Biomedical |
submitter keyword: LC-MSMS, IL-1, cartilage explant, TMT,Horse |
Contact List
Ulla Ruetschi |
contact affiliation | Department of clinical chemistry, Institute of Biomedicine, The Sahlgrenska Academy at Gothenburg University |
contact email | ulla.ruetschi@clinchem.gu.se |
lab head | |
Ulla Rüetschi |
contact affiliation | Sahlgrenska University Hospital |
contact email | ulla.ruetschi@clinchem.gu.se |
dataset submitter | |
Full Dataset Link List
Dataset FTP location
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PRIDE project URI |
Repository Record List
[ + ]
[ - ]
- PRIDE
- PXD004993
- Label: PRIDE project
- Name: Equine OA model - An inflammatory equine model demonstrates dynamic changes of immune response and cartilage matrix molecule degradation in vitro