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PXD004993

PXD004993 is an original dataset announced via ProteomeXchange.

Dataset Summary
TitleEquine OA model - An inflammatory equine model demonstrates dynamic changes of immune response and cartilage matrix molecule degradation in vitro
DescriptionArticular cartilage explants were incubated with or without interleukin-1β for 25 days. Media samples collected at 3-day intervals were analysed by quantitative proteomics. Semi-tryptic COMP peptides containing novel neo-epitopes were identified and quantified in cell culture media from cartilage explants.
HostingRepositoryPRIDE
AnnounceDate2024-10-22
AnnouncementXMLSubmission_2024-10-22_04:09:11.201.xml
DigitalObjectIdentifier
ReviewLevelPeer-reviewed dataset
DatasetOriginOriginal dataset
RepositorySupportUnsupported dataset by repository
PrimarySubmitterUlla Rüetschi
SpeciesList scientific name: Equus caballus (Horse); NCBI TaxID: 9796;
ModificationListiodoacetamide derivatized residue
InstrumentLTQ Orbitrap
Dataset History
RevisionDatetimeStatusChangeLog Entry
02016-09-19 02:48:11ID requested
12018-01-05 01:29:54announced
22024-10-22 04:09:27announced2024-10-22: Updated project metadata.
Publication List
10.3109/03008207.2015.1027340;
Svala E, L, ö, fgren M, Sihlbom C, R, ü, etschi U, Lindahl A, Ekman S, Ski, ö, ldebrand E, An inflammatory equine model demonstrates dynamic changes of immune response and cartilage matrix molecule degradation in vitro. Connect Tissue Res, 56(4):315-25(2015) [pubmed]
10.1111/evj.12666;
Ski, ö, ldebrand E, Ekman S, Mattsson Hult, é, n L, Svala E, Bj, ö, rkman K, Lindahl A, Lundqvist A, Ö, nnerfjord P, Sihlbom C, R, ü, etschi U, Cartilage oligomeric matrix protein neoepitope in the synovial fluid of horses with acute lameness: A new biomarker for the early stages of osteoarthritis. Equine Vet J, 49(5):662-667(2017) [pubmed]
Keyword List
curator keyword: Biomedical
submitter keyword: LC-MSMS, IL-1, cartilage explant, TMT,Horse
Contact List
Ulla Ruetschi
contact affiliationDepartment of clinical chemistry, Institute of Biomedicine, The Sahlgrenska Academy at Gothenburg University
contact emailulla.ruetschi@clinchem.gu.se
lab head
Ulla Rüetschi
contact affiliationSahlgrenska University Hospital
contact emailulla.ruetschi@clinchem.gu.se
dataset submitter
Full Dataset Link List
Dataset FTP location
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PRIDE project URI
Repository Record List
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