PXD004993

PXD004993 is an original dataset announced via ProteomeXchange.

Dataset Summary

Title	Equine OA model - An inflammatory equine model demonstrates dynamic changes of immune response and cartilage matrix molecule degradation in vitro
Description	Articular cartilage explants were incubated with or without interleukin-1β for 25 days. Media samples collected at 3-day intervals were analysed by quantitative proteomics. Semi-tryptic COMP peptides containing novel neo-epitopes were identified and quantified in cell culture media from cartilage explants.
HostingRepository	PRIDE
AnnounceDate	2024-10-22
AnnouncementXML	Submission_2024-10-22_04:09:11.201.xml
DigitalObjectIdentifier
ReviewLevel	Peer-reviewed dataset
DatasetOrigin	Original dataset
RepositorySupport	Unsupported dataset by repository
PrimarySubmitter	Ulla Rüetschi
SpeciesList	scientific name: Equus caballus (Horse); NCBI TaxID: 9796;
ModificationList	iodoacetamide derivatized residue
Instrument	LTQ Orbitrap

Dataset History

Revision	Datetime	Status	ChangeLog Entry
0	2016-09-19 02:48:11	ID requested
1	2018-01-05 01:29:54	announced
⏵ 2	2024-10-22 04:09:27	announced	2024-10-22: Updated project metadata.

Publication List

10.3109/03008207.2015.1027340;
Svala E, L, ö, fgren M, Sihlbom C, R, ü, etschi U, Lindahl A, Ekman S, Ski, ö, ldebrand E, An inflammatory equine model demonstrates dynamic changes of immune response and cartilage matrix molecule degradation in vitro. Connect Tissue Res, 56(4):315-25(2015) [pubmed]
10.1111/evj.12666;
Ski, ö, ldebrand E, Ekman S, Mattsson Hult, é, n L, Svala E, Bj, ö, rkman K, Lindahl A, Lundqvist A, Ö, nnerfjord P, Sihlbom C, R, ü, etschi U, Cartilage oligomeric matrix protein neoepitope in the synovial fluid of horses with acute lameness: A new biomarker for the early stages of osteoarthritis. Equine Vet J, 49(5):662-667(2017) [pubmed]

10.3109/03008207.2015.1027340;

Svala E, L, ö, fgren M, Sihlbom C, R, ü, etschi U, Lindahl A, Ekman S, Ski, ö, ldebrand E, An inflammatory equine model demonstrates dynamic changes of immune response and cartilage matrix molecule degradation in vitro. Connect Tissue Res, 56(4):315-25(2015) [pubmed]

10.1111/evj.12666;

Ski, ö, ldebrand E, Ekman S, Mattsson Hult, é, n L, Svala E, Bj, ö, rkman K, Lindahl A, Lundqvist A, Ö, nnerfjord P, Sihlbom C, R, ü, etschi U, Cartilage oligomeric matrix protein neoepitope in the synovial fluid of horses with acute lameness: A new biomarker for the early stages of osteoarthritis. Equine Vet J, 49(5):662-667(2017) [pubmed]

Keyword List

curator keyword: Biomedical
submitter keyword: LC-MSMS, IL-1, cartilage explant, TMT,Horse

curator keyword: Biomedical

submitter keyword: LC-MSMS, IL-1, cartilage explant, TMT,Horse

Contact List

Ulla Ruetschi
contact affiliation	Department of clinical chemistry, Institute of Biomedicine, The Sahlgrenska Academy at Gothenburg University
contact email	ulla.ruetschi@clinchem.gu.se
lab head
Ulla Rüetschi
contact affiliation	Sahlgrenska University Hospital
contact email	ulla.ruetschi@clinchem.gu.se
dataset submitter

Full Dataset Link List

Dataset FTP location NOTE: Most web browsers have now discontinued native support for FTP access within the browser window. But you can usually install another FTP app (we recommend FileZilla) and configure your browser to launch the external application when you click on this FTP link. Or otherwise, launch an app that supports FTP (like FileZilla) and use this address: ftp://ftp.pride.ebi.ac.uk/pride/data/archive/2018/01/PXD004993
PRIDE project URI

Dataset FTP location
NOTE: Most web browsers have now discontinued native support for FTP access within the browser window. But you can usually install another FTP app (we recommend FileZilla) and configure your browser to launch the external application when you click on this FTP link. Or otherwise, launch an app that supports FTP (like FileZilla) and use this address: ftp://ftp.pride.ebi.ac.uk/pride/data/archive/2018/01/PXD004993

PRIDE project URI

Repository Record List

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