PXD004981

PXD004981 is an original dataset announced via ProteomeXchange.

Title	Lapatinib action and resistance in breast cancer
Description	We used an established cell line model of lapatinib resistance and employed explorative mass spectrometry to profile the proteome, kinome and phosphoproteome changes in an effort to systematically investigate initial inhibitor response and concomitant kinome reprogramming and signaling rewiring in resistance. Experiments were performed in three biological replicates
HostingRepository	PRIDE
AnnounceDate	2024-10-22
AnnouncementXML	Submission_2024-10-22_04:10:19.272.xml
DigitalObjectIdentifier
ReviewLevel	Peer-reviewed dataset
DatasetOrigin	Original dataset
RepositorySupport	Unsupported dataset by repository
PrimarySubmitter	Benjamin Ruprecht
SpeciesList	scientific name: Homo sapiens (Human); NCBI TaxID: 9606;
ModificationList	phosphorylated residue; monohydroxylated residue; iodoacetamide derivatized residue
Instrument	Q Exactive

Revision	Datetime	Status	ChangeLog Entry
0	2016-09-16 00:52:18	ID requested
1	2017-02-27 06:37:43	announced
⏵ 2	2024-10-22 04:10:19	announced	2024-10-22: Updated project metadata.

Dataset with its publication pending

submitter keyword: Metabolomics, Mass Spectrometry,Phosphoproteomics, Breast Cancer, Drug Resistance

Simone Lemeer
contact affiliation	Biomolecular Mass Spectrometry and Proteomics, Bijvoet Center for Biomolecular Research and Utrecht Institute of Pharmaceutical Sciences, Utrecht University, Utrecht, The Netherlands
contact email	S.M.Lemeer@uu.nl
lab head
Benjamin Ruprecht
contact affiliation	TUM
contact email	Benjamin.Ruprecht@tum.de
dataset submitter

Dataset FTP location NOTE: Most web browsers have now discontinued native support for FTP access within the browser window. But you can usually install another FTP app (we recommend FileZilla) and configure your browser to launch the external application when you click on this FTP link. Or otherwise, launch an app that supports FTP (like FileZilla) and use this address: ftp://ftp.pride.ebi.ac.uk/pride/data/archive/2017/02/PXD004981

PRIDE project URI

• PRIDE
  1. PXD004981
     1. Label: PRIDE project
     2. Name: Lapatinib action and resistance in breast cancer