PXD004908

PXD004908 is an original dataset announced via ProteomeXchange.

Title	Brown bear skeletal muscle quantitative LC-MSMS
Description	Muscle atrophy is one of the main deleterious consequences of ageing and physical inactivity. Although basic knowledge regarding the underlying mechanisms of muscle atrophy is continuously growing, there are still no efficient therapeutic strategies for its prevention and treatment. Hibernating bears exhibit a strong and unique ability to preserve muscle mass in conditions where muscle atrophy is observed in humans. However, underlying mechanisms have not been understood yet. To fill this gap, the aim of this study was to characterize changes in the bear muscle proteome during hibernation versus the active period. Muscle biopsies were obtained from Ursus arctos bears.
HostingRepository	PRIDE
AnnounceDate	2019-05-15
AnnouncementXML	Submission_2019-09-02_00:03:49.xml
DigitalObjectIdentifier
ReviewLevel	Peer-reviewed dataset
DatasetOrigin	Original dataset
RepositorySupport	Unsupported dataset by repository
PrimarySubmitter	Fabrice BERTILE
SpeciesList	scientific name: Ursus arctos (Brown bear) (Grizzly bear); NCBI TaxID: 9644;
ModificationList	monohydroxylated residue; acetylated residue; iodoacetamide derivatized residue
Instrument	maXis 4G

Revision	Datetime	Status	ChangeLog Entry
0	2016-09-10 14:46:18	ID requested
1	2019-05-15 02:58:32	announced
⏵ 2	2019-09-02 00:03:51	announced	Updated publication reference for PubMed record(s): 31443506, 31080489.

Chazarin B, Storey KB, Ziemianin A, Chanon S, Plumel M, Chery I, Durand C, Evans AL, Arnemo JM, Zedrosser A, Swenson JE, Gauquelin-Koch G, Simon C, Blanc S, Lefai E, Bertile F, Metabolic reprogramming involving glycolysis in the hibernating brown bear skeletal muscle. Front Zool, 16():12(2019) [pubmed]

Chazarin B, Ziemianin A, Evans AL, Meugnier E, Loizon E, Chery I, Arnemo JM, Swenson JE, Gauquelin-Koch G, Simon C, Blanc S, Lefai E, Bertile F, ). Antioxidants (Basel), 8(9):(2019) [pubmed]

curator keyword: Biological

submitter keyword: Bears, skeletal muscle, hibernation, LC-MSMS

Sarah Cianférani
contact affiliation	Laboratoire de Spectrométrie de Masse BioOrganique, Analytical Science department, IPHC, CNRS, Strasbourg University, UMR7178, Strasbourg, France
contact email	sarah.cianferani@unistra.fr
lab head
Fabrice BERTILE
contact affiliation	CNRS
contact email	fbertile@unistra.fr
dataset submitter

Dataset FTP location NOTE: Most web browsers have now discontinued native support for FTP access within the browser window. But you can usually install another FTP app (we recommend FileZilla) and configure your browser to launch the external application when you click on this FTP link. Or otherwise, launch an app that supports FTP (like FileZilla) and use this address: ftp://ftp.pride.ebi.ac.uk/pride/data/archive/2019/05/PXD004908

PRIDE project URI

• PRIDE
  1. PXD004908
     1. Label: PRIDE project
     2. Name: Brown bear skeletal muscle quantitative LC-MSMS