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PXD004818

PXD004818 is an original dataset announced via ProteomeXchange.

Dataset Summary
TitleSpectral histopathology supported laser capture microdissection and quantitative proteome analysis of diffuse malignant mesothelioma
DescriptionFTIR based spectral histopathology was used for label-free classification of tumor tissue sections. The regions of interest were identified and annotated with high spatial resolution. The spatial information was used for automated laser capture microdissection of relevant tissue areas. Subsequently, the collected tissue samples were analyzed using quantitative proteomics. This novel approach for precise sample collection in clinical studies was applied to differentiate epitheloid and sarcomatoid subtypes of diffuse malignant mesothelioma.
HostingRepositoryPRIDE
AnnounceDate2017-03-31
AnnouncementXMLSubmission_2017-03-31_04:27:30.xml
DigitalObjectIdentifierhttps://dx.doi.org/10.6019/PXD004818
ReviewLevelPeer-reviewed dataset
DatasetOriginOriginal dataset
RepositorySupportSupported dataset by repository
PrimarySubmitterThilo Bracht
SpeciesList scientific name: Homo sapiens (Human); NCBI TaxID: 9606;
ModificationListresidues isobaric at 128.058578 Da; Oxidation; Carbamidomethyl
InstrumentLTQ Orbitrap Elite
Dataset History
RevisionDatetimeStatusChangeLog Entry
02016-08-16 01:21:59ID requested
12017-03-31 04:27:31announced
Publication List
Gro, ß, erueschkamp F, Bracht T, Diehl HC, Kuepper C, Ahrens M, Kallenbach-Thieltges A, Mosig A, Eisenacher M, Marcus K, Behrens T, Br, ü, ning T, Theegarten D, Sitek B, Gerwert K, Spatial and molecular resolution of diffuse malignant mesothelioma heterogeneity by integrating label-free FTIR imaging, laser capture microdissection and proteomics. Sci Rep, 7():44829(2017) [pubmed]
Keyword List
curator keyword: Biomedical
submitter keyword: Colorectal carcinoma, diffuse malignant mesothelioma, laser capture microdissection, infrared spectral histopathology, FTIR
Contact List
Barbara Sitek
contact affiliationRuhr-Universität Bochum Medizinisches Proteom-Center AG Clinical Proteomics
contact emailbarbara.sitek@rub.de
lab head
Thilo Bracht
contact affiliationClinical Proteomics
contact emailthilo.bracht@rub.de
dataset submitter
Full Dataset Link List
Dataset FTP location
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PRIDE project URI
Repository Record List
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