PXD004798

PXD004798 is an original dataset announced via ProteomeXchange.

Title	Chemical proteomics to elucidate target proteins of cysteine-stabilized and circular peptides
Description	Cyclotides are circular and cystine-rich peptides which are little amenable to chemical modifications for probe design in chemical biology. The cyclotide [T20K]kalata B1 is an immune system modulating drug reported for its therapeutic application in multiple sclerosis.
HostingRepository	PRIDE
AnnounceDate	2017-09-26
AnnouncementXML	Submission_2017-10-30_03:25:29.xml
DigitalObjectIdentifier	https://dx.doi.org/10.6019/PXD004798
ReviewLevel	Peer-reviewed dataset
DatasetOrigin	Original dataset
RepositorySupport	Supported dataset by repository
PrimarySubmitter	Roland Hellinger
SpeciesList	scientific name: Mus musculus (Mouse); NCBI TaxID: 10090; scientific name: Homo sapiens (Human); NCBI TaxID: 9606;
ModificationList	Nitro; Phospho; Deamidated; Carbamidomethyl; Oxidation; Acetyl
Instrument	X500R QTOF

Revision	Datetime	Status	ChangeLog Entry
0	2016-08-15 02:35:32	ID requested
1	2017-09-26 07:31:35	announced
⏵ 2	2017-10-30 03:25:30	announced	Updated publication reference for PubMed record(s): 29075625.

Hellinger R, Thell K, Vasileva M, Muhammad T, Gunasekera S, K, ü, mmel D, G, ö, ransson U, Becker CW, Gruber CW, Chemical Proteomics for Target Discovery of Head-to-Tail Cyclized Mini-Proteins. Front Chem, 5():73(2017) [pubmed]

submitter keyword: target deconvolution, cyclotides, multiple sclerosis, peptide drug, target identification

Christian Werner Gruber
contact affiliation	Physiology and Pharmacology, Medical University of Vienna, Schwarzspanierstrasse 17, 1090 Vienna
contact email	christian.w.gruber@meduniwien.ac.at
lab head
Roland Hellinger
contact affiliation	Medical University of Vienna, Center for Pharmacology and Physiology
contact email	roland.hellinger@meduniwien.ac.at
dataset submitter

Dataset FTP location NOTE: Most web browsers have now discontinued native support for FTP access within the browser window. But you can usually install another FTP app (we recommend FileZilla) and configure your browser to launch the external application when you click on this FTP link. Or otherwise, launch an app that supports FTP (like FileZilla) and use this address: ftp://ftp.pride.ebi.ac.uk/pride/data/archive/2017/09/PXD004798

PRIDE project URI

• PRIDE
  1. PXD004798
     1. Label: PRIDE project
     2. Name: Chemical proteomics to elucidate target proteins of cysteine-stabilized and circular peptides