PXD004709

PXD004709 is an original dataset announced via ProteomeXchange.

Dataset Summary

Title	Proteomic profiles of Rat Pancreatic Islets
Description	In this study, we achieved integrated transcriptomic and proteomic profiles of GK islets in a time-course fashion at different stages of T2D. Subsequent bioinformatics analysis revealed the chronological order of T2D-related molecular events during the deterioration of pancreatic islets. Our large quantitative dataset provide a valuable resource to obtain a comprehensive picture of the mechanisms responsible for islet dysfunction and to identify potential interventions to prevent beta-cell failure in human T2D.
HostingRepository	PRIDE
AnnounceDate	2024-10-22
AnnouncementXML	Submission_2024-10-22_04:30:46.054.xml
DigitalObjectIdentifier
ReviewLevel	Peer-reviewed dataset
DatasetOrigin	Original dataset
RepositorySupport	Unsupported dataset by repository
PrimarySubmitter	JUNJIE HOU
SpeciesList	scientific name: Rattus norvegicus (Rat); NCBI TaxID: 10116;
ModificationList	No PTMs are included in the dataset
Instrument	Q Exactive

Dataset History

Revision	Datetime	Status	ChangeLog Entry
0	2016-08-03 03:50:16	ID requested
1	2017-06-02 04:48:31	announced
⏵ 2	2024-10-22 04:30:54	announced	2024-10-22: Updated project metadata.

Publication List

10.2337/db16-1305;
Hou J, Li Z, Zhong W, Hao Q, Lei L, Wang L, Zhao D, Xu P, Zhou Y, Wang Y, Xu T, Temporal Transcriptomic and Proteomic Landscapes of Deteriorating Pancreatic Islets in Type 2 Diabetic Rats. Diabetes, 66(8):2188-2200(2017) [pubmed]

10.2337/db16-1305;

Hou J, Li Z, Zhong W, Hao Q, Lei L, Wang L, Zhao D, Xu P, Zhou Y, Wang Y, Xu T, Temporal Transcriptomic and Proteomic Landscapes of Deteriorating Pancreatic Islets in Type 2 Diabetic Rats. Diabetes, 66(8):2188-2200(2017) [pubmed]

Keyword List

curator keyword: Biological
submitter keyword: Rat Islets proteome

curator keyword: Biological

submitter keyword: Rat Islets proteome

Contact List

TAO XU
contact affiliation	THE INSTITUTE OF BIOPHYSICS, CAS
contact email	xutao@ibp.ac.cn
lab head
JUNJIE HOU
contact affiliation	THE INSTITUTE OF BIOPHYSICS, CAS
contact email	houjunjie@moon.ibp.ac.cn
dataset submitter

Full Dataset Link List

Dataset FTP location NOTE: Most web browsers have now discontinued native support for FTP access within the browser window. But you can usually install another FTP app (we recommend FileZilla) and configure your browser to launch the external application when you click on this FTP link. Or otherwise, launch an app that supports FTP (like FileZilla) and use this address: ftp://ftp.pride.ebi.ac.uk/pride/data/archive/2017/06/PXD004709
PRIDE project URI

Dataset FTP location
NOTE: Most web browsers have now discontinued native support for FTP access within the browser window. But you can usually install another FTP app (we recommend FileZilla) and configure your browser to launch the external application when you click on this FTP link. Or otherwise, launch an app that supports FTP (like FileZilla) and use this address: ftp://ftp.pride.ebi.ac.uk/pride/data/archive/2017/06/PXD004709

PRIDE project URI

Repository Record List

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