PXD004696

PXD004696 is an original dataset announced via ProteomeXchange.

Dataset Summary

Title	Comprehensive identification of proteins expressed by human oligodendroglia cell line
Description	Oligodendrocytes are a type of neuroglia that have provide trophic support and insulation to axons in central nervous system. A proper differentiation of oligodendrocyte precursor cells is crucial for central nervous system myelination and development. Such maturation proccess can be induced in vitro by addition of 12-myristate 13-acetate (PMA) jointly to serum deprivation in oligodendrocyte precursor cell cultures. In the present work, we established a reference data set using 2D LC fractionation and ion-mobility enhanced data-independent proteomic analyses of proteins expressed by treated- and nontreated oligodendrocytes. The final dataset beyond all fractions comprised 223,531 ion peptides corresponding to 10,614 proteins groups. Our results can help futher studies using MO3.13 cells as a tool of investigation not only to oligodendrocyte maturation, also to diseases that have oligodendrocytes as key players.
HostingRepository	PRIDE
AnnounceDate	2024-10-22
AnnouncementXML	Submission_2024-10-22_04:31:30.605.xml
DigitalObjectIdentifier
ReviewLevel	Peer-reviewed dataset
DatasetOrigin	Original dataset
RepositorySupport	Unsupported dataset by repository
PrimarySubmitter	Juliana Cassoli
SpeciesList	scientific name: Homo sapiens (Human); NCBI TaxID: 9606;
ModificationList	iodoacetamide derivatized residue
Instrument	Synapt MS

Dataset History

Revision	Datetime	Status	ChangeLog Entry
0	2016-08-01 08:36:01	ID requested
1	2017-09-27 00:21:53	announced
⏵ 2	2024-10-22 04:31:31	announced	2024-10-22: Updated project metadata.

Publication List

S Cassoli J, Brand, ã, o-Teles C, G Santana A, H M F Souza G, Martins-de-Souza D, Ion Mobility-Enhanced Data-Independent Acquisitions Enable a Deep Proteomic Landscape of Oligodendrocytes. Proteomics, 17(21):(2017) [pubmed]
10.1002/pmic.201700209;

S Cassoli J, Brand, ã, o-Teles C, G Santana A, H M F Souza G, Martins-de-Souza D, Ion Mobility-Enhanced Data-Independent Acquisitions Enable a Deep Proteomic Landscape of Oligodendrocytes. Proteomics, 17(21):(2017) [pubmed]

10.1002/pmic.201700209;

Keyword List

curator keyword: Biological
submitter keyword: UDMSE,Proteome, Oligodendrocytes

curator keyword: Biological

submitter keyword: UDMSE,Proteome, Oligodendrocytes

Contact List

Daniel Martins de Souza
contact affiliation	Department of Biochemistry and Tissue Biology, Institute of Biology, University of Campinas (UNICAMP)
contact email	dmsouza@unicamp.br
lab head
Juliana Cassoli
contact affiliation	University of Campinas
contact email	jscassoli@gmail.com
dataset submitter

Full Dataset Link List

Dataset FTP location NOTE: Most web browsers have now discontinued native support for FTP access within the browser window. But you can usually install another FTP app (we recommend FileZilla) and configure your browser to launch the external application when you click on this FTP link. Or otherwise, launch an app that supports FTP (like FileZilla) and use this address: ftp://ftp.pride.ebi.ac.uk/pride/data/archive/2017/09/PXD004696
PRIDE project URI

Dataset FTP location
NOTE: Most web browsers have now discontinued native support for FTP access within the browser window. But you can usually install another FTP app (we recommend FileZilla) and configure your browser to launch the external application when you click on this FTP link. Or otherwise, launch an app that supports FTP (like FileZilla) and use this address: ftp://ftp.pride.ebi.ac.uk/pride/data/archive/2017/09/PXD004696

PRIDE project URI

Repository Record List

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