PXD004612

PXD004612 is an original dataset announced via ProteomeXchange.

Title	Proteomic comparison study between female and male tendon
Description	Tendons play fundamental role in the musculoskeletal system and locomotion by transferring forces generated by muscles to the skeleton. Chronic tendon injuries and diseases are among the leading causes of musculoskeletal disability. For many types of tendinopathies, women have worse clinical outcomes than men. It is possible that tendon sex-based differences in protein composition are related to an altered injury response. The aim of this study was to compare the proteome of male and female tendon using label-free protein quantification. These data could provide new insight into pathways which may beinvolved in tendinopathies, and potentially in the differential injury response of female tendon.
HostingRepository	PRIDE
AnnounceDate	2017-01-16
AnnouncementXML	Submission_2017-01-16_11:55:32.xml
DigitalObjectIdentifier	https://dx.doi.org/10.6019/PXD004612
ReviewLevel	Peer-reviewed dataset
DatasetOrigin	Original dataset
RepositorySupport	Supported dataset by repository
PrimarySubmitter	Yalda Ashraf
SpeciesList	scientific name: Mus musculus (Mouse); NCBI TaxID: 10090;
ModificationList	Oxidation; Carbamidomethyl
Instrument	Q Exactive

Revision	Datetime	Status	ChangeLog Entry
0	2016-07-20 06:07:30	ID requested
⏵ 1	2017-01-16 11:55:34	announced

Sarver DC, Kharaz YA, Sugg KB, Gumucio JP, Comerford E, Mendias CL, Sex differences in tendon structure and function. J Orthop Res, 35(10):2117-2126(2017) [pubmed]

curator keyword: Biological, Biomedical

submitter keyword: tendon, female, male, LC-MS/MS

Dr. Chris Mendias
contact affiliation	Department of Orthopaedic Surgery, University of Michigan Ann Arbor, Michigan, USA
contact email	cmendias@umich.edu
lab head
Yalda Ashraf
contact affiliation	University of Liverpool
contact email	yalda@liverpool.ac.uk
dataset submitter

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PRIDE project URI

• PRIDE
  1. PXD004612
     1. Label: PRIDE project
     2. Name: Proteomic comparison study between female and male tendon