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PXD004574

PXD004574 is an original dataset announced via ProteomeXchange.

Dataset Summary
TitleInference and quantification of peptidoforms in large sample cohorts by SWATH-MS: Twin blood plasma quantitative variance components
DescriptionThis data set represents a reanalysis of human blood plasma samples measured by SWATH-MS of 36 pairs of monozygotic and 22 pairs of dizygotic twins that were sampled at two longitudinal time points (Liu et al., 2015, PMID:25652787). The data were used to determine the overall quantitative variability of 4322 peptidoforms in the sample cohort and to assign the measured variability to heritability, environmental or longitudinal effects.
HostingRepositoryPRIDE
AnnounceDate2024-10-22
AnnouncementXMLSubmission_2024-10-22_04:31:49.185.xml
DigitalObjectIdentifier
ReviewLevelPeer-reviewed dataset
DatasetOriginOriginal dataset
RepositorySupportUnsupported dataset by repository
PrimarySubmitterGeorge Rosenberger
SpeciesList scientific name: Homo sapiens (Human); NCBI TaxID: 9606;
ModificationListmonomethylated residue; carboxylated residue; phosphorylated residue; 6x(13)C labeled residue; acetylated residue; iodoacetamide derivatized residue; deamidated residue; carbamoylated residue; sulfated residue; amidated residue; nitrated residue; ubiquitination signature dipeptidyl lysine; monohydroxylated residue; formylated residue
InstrumentTripleTOF 5600
Dataset History
RevisionDatetimeStatusChangeLog Entry
02016-07-14 03:01:56ID requested
12017-06-06 08:45:23announced
22017-06-19 08:20:29announcedUpdated publication reference for PubMed record(s): 25652787, 28604659.
32024-10-22 04:32:05announced2024-10-22: Updated project metadata.
Publication List
Liu Y, Buil A, Collins BC, Gillet LC, Blum LC, Cheng LY, Vitek O, Mouritsen J, Lachance G, Spector TD, Dermitzakis ET, Aebersold R, Quantitative variability of 342 plasma proteins in a human twin population. Mol Syst Biol, 11(1):786(2015) [pubmed]
10.1038/nbt.3908;
Rosenberger G, Liu Y, R, ö, st HL, Ludwig C, Buil A, Bensimon A, Soste M, Spector TD, Dermitzakis ET, Collins BC, Malmstr, ö, m L, Aebersold R, Inference and quantification of peptidoforms in large sample cohorts by SWATH-MS. Nat Biotechnol, 35(8):781-788(2017) [pubmed]
Keyword List
curator keyword: Technical, Biomedical
submitter keyword: IPF, OpenSWATH, blood plasma, PTM,human
Contact List
Ruedi Aebersold
contact affiliationInstitute of Molecular Systems Biology ETH Zurich Switzerland
contact emailaebersold@imsb.biol.ethz.ch
lab head
George Rosenberger
contact affiliationColumbia University
contact emailgr2578@cumc.columbia.edu
dataset submitter
Full Dataset Link List
Dataset FTP location
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PRIDE project URI
Repository Record List
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