PXD004574

PXD004574 is an original dataset announced via ProteomeXchange.

Title	Inference and quantification of peptidoforms in large sample cohorts by SWATH-MS: Twin blood plasma quantitative variance components
Description	This data set represents a reanalysis of human blood plasma samples measured by SWATH-MS of 36 pairs of monozygotic and 22 pairs of dizygotic twins that were sampled at two longitudinal time points (Liu et al., 2015, PMID:25652787). The data were used to determine the overall quantitative variability of 4322 peptidoforms in the sample cohort and to assign the measured variability to heritability, environmental or longitudinal effects.
HostingRepository	PRIDE
AnnounceDate	2024-10-22
AnnouncementXML	Submission_2024-10-22_04:31:49.185.xml
DigitalObjectIdentifier
ReviewLevel	Peer-reviewed dataset
DatasetOrigin	Original dataset
RepositorySupport	Unsupported dataset by repository
PrimarySubmitter	George Rosenberger
SpeciesList	scientific name: Homo sapiens (Human); NCBI TaxID: 9606;
ModificationList	monomethylated residue; carboxylated residue; phosphorylated residue; 6x(13)C labeled residue; acetylated residue; iodoacetamide derivatized residue; deamidated residue; carbamoylated residue; sulfated residue; amidated residue; nitrated residue; ubiquitination signature dipeptidyl lysine; monohydroxylated residue; formylated residue
Instrument	TripleTOF 5600

Revision	Datetime	Status	ChangeLog Entry
0	2016-07-14 03:01:56	ID requested
1	2017-06-06 08:45:23	announced
2	2017-06-19 08:20:29	announced	Updated publication reference for PubMed record(s): 25652787, 28604659.
⏵ 3	2024-10-22 04:32:05	announced	2024-10-22: Updated project metadata.

Liu Y, Buil A, Collins BC, Gillet LC, Blum LC, Cheng LY, Vitek O, Mouritsen J, Lachance G, Spector TD, Dermitzakis ET, Aebersold R, Quantitative variability of 342 plasma proteins in a human twin population. Mol Syst Biol, 11(1):786(2015) [pubmed]

10.1038/nbt.3908;

Rosenberger G, Liu Y, R, ö, st HL, Ludwig C, Buil A, Bensimon A, Soste M, Spector TD, Dermitzakis ET, Collins BC, Malmstr, ö, m L, Aebersold R, Inference and quantification of peptidoforms in large sample cohorts by SWATH-MS. Nat Biotechnol, 35(8):781-788(2017) [pubmed]

curator keyword: Technical, Biomedical

submitter keyword: IPF, OpenSWATH, blood plasma, PTM,human

Ruedi Aebersold
contact affiliation	Institute of Molecular Systems Biology ETH Zurich Switzerland
contact email	aebersold@imsb.biol.ethz.ch
lab head
George Rosenberger
contact affiliation	Columbia University
contact email	gr2578@cumc.columbia.edu
dataset submitter

Dataset FTP location NOTE: Most web browsers have now discontinued native support for FTP access within the browser window. But you can usually install another FTP app (we recommend FileZilla) and configure your browser to launch the external application when you click on this FTP link. Or otherwise, launch an app that supports FTP (like FileZilla) and use this address: ftp://ftp.pride.ebi.ac.uk/pride/data/archive/2017/06/PXD004574

PRIDE project URI

• PRIDE
  1. PXD004574
     1. Label: PRIDE project
     2. Name: Inference and quantification of peptidoforms in large sample cohorts by SWATH-MS: Twin blood plasma quantitative variance components