PXD004540

PXD004540 is an original dataset announced via ProteomeXchange.

Title	Multiple sclerosis biomarker discovery in cerebrospinal fluid using glycopeptide enrichment, TMT labeling and LC-MS/MS
Description	Multiple sclerosis biomarker discovery in pooled cerebrospinal fluid (CSF) using glycopeptide enrichment, TMT labeling and LC-MS/MS. Comparing 3 pools of CSF from relapsing-remitting MS (RRMS) patients to 3 pools of CSF from patients with other neurological diseases (OND). To reveal protein groups and networks affected by MS and to look at correlation between a glyco and a global approach.
HostingRepository	PRIDE
AnnounceDate	2017-10-24
AnnouncementXML	Submission_2017-10-24_01:54:00.xml
DigitalObjectIdentifier	https://dx.doi.org/10.6019/PXD004540
ReviewLevel	Peer-reviewed dataset
DatasetOrigin	Original dataset
RepositorySupport	Supported dataset by repository
PrimarySubmitter	Astrid Guldbrandsen
SpeciesList	scientific name: Homo sapiens (Human); NCBI TaxID: 9606;
ModificationList	Glu->pyro-Glu; Deamidated; TMT6plex; Oxidation; Acetyl; Carbamidomethyl; Gln->pyro-Glu
Instrument	Q Exactive

Revision	Datetime	Status	ChangeLog Entry
0	2016-07-11 02:16:26	ID requested
1	2016-10-13 07:23:13	announced
⏵ 2	2017-10-24 01:54:01	announced	Updated project metadata.

Kroksveen AC, Guldbrandsen A, Vaudel M, Lereim RR, Barsnes H, Myhr KM, Torkildsen Ø, Berven FS, In-Depth Cerebrospinal Fluid Quantitative Proteome and Deglycoproteome Analysis: Presenting a Comprehensive Picture of Pathways and Processes Affected by Multiple Sclerosis. J Proteome Res, 16(1):179-194(2017) [pubmed]

curator keyword: Biomedical

submitter keyword: Human, Cerebrospinal Fluid, LC-MS/MS, Discovery, TMT, Glycopeptide enrichment

Frode S. Berven
contact affiliation	Proteomics unit (PROBE), Department of Biomedicine, University of Bergen, Norway
contact email	Frode.Berven@uib.no
lab head
Astrid Guldbrandsen
contact affiliation	University of Bergen
contact email	astrid.guldbrandsen@uib.no
dataset submitter

Dataset FTP location NOTE: Most web browsers have now discontinued native support for FTP access within the browser window. But you can usually install another FTP app (we recommend FileZilla) and configure your browser to launch the external application when you click on this FTP link. Or otherwise, launch an app that supports FTP (like FileZilla) and use this address: ftp://ftp.pride.ebi.ac.uk/pride/data/archive/2016/10/PXD004540

PRIDE project URI

• PRIDE
  1. PXD004540
     1. Label: PRIDE project
     2. Name: Multiple sclerosis biomarker discovery in cerebrospinal fluid using glycopeptide enrichment, TMT labeling and LC-MS/MS