PXD004514

PXD004514 is an original dataset announced via ProteomeXchange.

Dataset Summary

Title	S-Sulfenylation regulates non-enzymatic oxidative protein folding
Description	The post-translational modification S-Sulfenylation functions as a key sensor of oxidative stress yet the dynamics of sulfenic acids in proteins is largely elusive due to it's fleeting nature. LC-MS/MS analysis has detected the evolution of this modification in oxidative and reducing states.
HostingRepository	PRIDE
AnnounceDate	2024-10-22
AnnouncementXML	Submission_2024-10-22_04:17:17.080.xml
DigitalObjectIdentifier
ReviewLevel	Peer-reviewed dataset
DatasetOrigin	Original dataset
RepositorySupport	Unsupported dataset by repository
PrimarySubmitter	Steven Lynham
SpeciesList	scientific name: Homo sapiens (Human); NCBI TaxID: 9606;
ModificationList	acetylated residue; monohydroxylated residue; iodoacetamide derivatized residue
Instrument	LTQ Orbitrap Velos

Dataset History

Revision	Datetime	Status	ChangeLog Entry
0	2016-07-05 05:21:16	ID requested
1	2017-01-03 03:14:58	announced
2	2017-10-24 03:37:22	announced	Updated project metadata.
⏵ 3	2024-10-22 04:17:17	announced	2024-10-22: Updated project metadata.

Publication List

Beedle AE, Lynham S, Garcia-Manyes S, Protein S-sulfenylation is a fleeting molecular switch that regulates non-enzymatic oxidative folding. Nat Commun, 7():12490(2016) [pubmed]
10.1038/ncomms12490;

Beedle AE, Lynham S, Garcia-Manyes S, Protein S-sulfenylation is a fleeting molecular switch that regulates non-enzymatic oxidative folding. Nat Commun, 7():12490(2016) [pubmed]

10.1038/ncomms12490;

Keyword List

curator keyword: Biological
submitter keyword: LC-MS/MS, post-translational modifications, human titin

curator keyword: Biological

submitter keyword: LC-MS/MS, post-translational modifications, human titin

Contact List

Sergi Garcia-Manyes
contact affiliation	King's College London; Physics Department
contact email	sergi.garcia-manyes@kcl.ac.uk
lab head
Steven Lynham
contact affiliation	King's College London
contact email	steven.lynham@kcl.ac.uk
dataset submitter

Full Dataset Link List

Dataset FTP location NOTE: Most web browsers have now discontinued native support for FTP access within the browser window. But you can usually install another FTP app (we recommend FileZilla) and configure your browser to launch the external application when you click on this FTP link. Or otherwise, launch an app that supports FTP (like FileZilla) and use this address: ftp://ftp.pride.ebi.ac.uk/pride/data/archive/2016/12/PXD004514
PRIDE project URI

Dataset FTP location
NOTE: Most web browsers have now discontinued native support for FTP access within the browser window. But you can usually install another FTP app (we recommend FileZilla) and configure your browser to launch the external application when you click on this FTP link. Or otherwise, launch an app that supports FTP (like FileZilla) and use this address: ftp://ftp.pride.ebi.ac.uk/pride/data/archive/2016/12/PXD004514

PRIDE project URI

Repository Record List

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