PXD004499

PXD004499 is an original dataset announced via ProteomeXchange.

Title	Human temporal neocortex brain LC-MS
Description	We used label-free shotgun mass spectrometry to analyze temporal neocortex samples from AD brain, other neurological disorders and non-demented controls, in order to identify additional proteins thatare altered in AD. The mass spectrometry results were then verified by antibody suspension bead arrays.
HostingRepository	PRIDE
AnnounceDate	2016-09-29
AnnouncementXML	Submission_2016-09-29_07:22:26.xml
DigitalObjectIdentifier
ReviewLevel	Peer-reviewed dataset
DatasetOrigin	Original dataset
RepositorySupport	Unsupported dataset by repository
PrimarySubmitter	Payam Emami Khoonsari
SpeciesList	scientific name: Homo sapiens (Human); NCBI TaxID: 9606;
ModificationList	monohydroxylated residue; acetylated residue; iodoacetamide derivatized residue
Instrument	LTQ FT

Revision	Datetime	Status	ChangeLog Entry
0	2016-07-01 07:43:40	ID requested
⏵ 1	2016-09-29 07:22:27	announced

Musunuri S, Khoonsari PE, Mikus M, Wetterhall M, H, ä, ggmark-M, ä, nberg A, Lannfelt L, Erlandsson A, Bergquist J, Ingelsson M, Shevchenko G, Nilsson P, Kultima K, Increased Levels of Extracellular Microvesicle Markers and Decreased Levels of Endocytic/Exocytic Proteins in the Alzheimer's Disease Brain. J Alzheimers Dis, 54(4):1671-1686(2016) [pubmed]

curator keyword: Biomedical

submitter keyword: Alzheimer’s disease

mass spectrometry

Antibodies, Immobilized/chemistry

extracellular vesicles

exosomes

exocytosis

endocytosis.

Kim Kultima
contact affiliation	Department of Medical Sciences, Cancer Pharmacology and Computational Medicine, Uppsala University Academic Hospital, Uppsala, Sweden.
contact email	kim.kultima@medsci.uu.se
lab head
Payam Emami Khoonsari
contact affiliation	Uppsala University
contact email	Payam.emami@medsci.uu.se
dataset submitter

Dataset FTP location NOTE: Most web browsers have now discontinued native support for FTP access within the browser window. But you can usually install another FTP app (we recommend FileZilla) and configure your browser to launch the external application when you click on this FTP link. Or otherwise, launch an app that supports FTP (like FileZilla) and use this address: ftp://ftp.pride.ebi.ac.uk/pride/data/archive/2016/09/PXD004499

PRIDE project URI

• PRIDE
  1. PXD004499
     1. Label: PRIDE project
     2. Name: Human temporal neocortex brain LC-MS