PXD004443

PXD004443 is an original dataset announced via ProteomeXchange.

Title	Blood coagulation and complement activation interact to increase disease activity in systemic lupus erythematosus and coagulation D-Dimer combined with complement C4 is a biomarker of lupus activity
Description	This study was conducted to (1) find deregulation of certain pathways in SLE at multi-omics levels; (2) evaluate the associations among blood coagulation, complement activation, inflammatory responses and SLE disease severity; (3) develop biomarkers to facilitate better the assessment of the likelihood of lupus activity.
HostingRepository	PRIDE
AnnounceDate	2018-10-26
AnnouncementXML	Submission_2018-10-26_15:44:47.xml
DigitalObjectIdentifier
ReviewLevel	Peer-reviewed dataset
DatasetOrigin	Original dataset
RepositorySupport	Unsupported dataset by repository
PrimarySubmitter	shangbo xie
SpeciesList	scientific name: Homo sapiens (Human); NCBI TaxID: 9606;
ModificationList	iTRAQ8plex-116 reporter+balance reagent acylated residue; monohydroxylated residue; iodoacetamide derivatized residue
Instrument	Q Exactive

Revision	Datetime	Status	ChangeLog Entry
0	2016-06-27 02:41:06	ID requested
⏵ 1	2018-10-26 15:44:48	announced

Liang Y, Xie SB, Wu CH, Hu Y, Zhang Q, Li S, Fan YG, Leng RX, Pan HF, Xiong HB, Ye DQ, Coagulation cascade and complement system in systemic lupus erythematosus. Oncotarget, 9(19):14862-14881(2018) [pubmed]

curator keyword: Biomedical

submitter keyword: Systemic Lupus Erythematosus

Blood coagulation;iTRAQ

Dong-Qing Ye
contact affiliation	Department of Epidemiology and Biostatistics, School of Public Health, Anhui Medical University, 81 Meishan Road, Hefei, Anhui, 230032, PR China
contact email	yedongqingahmu@163.com
lab head
shangbo xie
contact affiliation	BGI
contact email	xieshb2013@163.com
dataset submitter

Dataset FTP location NOTE: Most web browsers have now discontinued native support for FTP access within the browser window. But you can usually install another FTP app (we recommend FileZilla) and configure your browser to launch the external application when you click on this FTP link. Or otherwise, launch an app that supports FTP (like FileZilla) and use this address: ftp://ftp.pride.ebi.ac.uk/pride/data/archive/2018/10/PXD004443

PRIDE project URI

• PRIDE
  1. PXD004443
     1. Label: PRIDE project
     2. Name: Blood coagulation and complement activation interact to increase disease activity in systemic lupus erythematosus and coagulation D-Dimer combined with complement C4 is a biomarker of lupus activity