PXD004434

PXD004434 is an original dataset announced via ProteomeXchange.

Title	Human milk oligosaccharides and infant fecal oligosaccharides
Description	In this study, we quantitated the disappearance of intact HMOs and characterized the glycan digestion products in the gut that are produced by the action of microbial enzymes on HMOs and glycoconjugates from breast milk. Oligosaccharides from fecal samples of exclusively breast-fed infants were extracted and profiled using nanoLC-MS. Intact HMOs were found in the fecal samples, additionally, other oligosaccharides were found corresponding to degraded HMOs and non-HMO based compounds. The latter compounds were fragments of N-glycans released through the cleavage of the linkage to the asparagine residue and through cleavage of the chitobiose core of the N-glycan.
HostingRepository	PRIDE
AnnounceDate	2016-07-26
AnnouncementXML	Submission_2016-07-26_03:12:52.xml
DigitalObjectIdentifier
ReviewLevel	Peer-reviewed dataset
DatasetOrigin	Original dataset
RepositorySupport	Unsupported dataset by repository
PrimarySubmitter	Jasmine Davis
SpeciesList	scientific name: Homo sapiens (Human); NCBI TaxID: 9606;
ModificationList	No PTMs are included in the dataset
Instrument	6520 Quadrupole Time-of-Flight LC/MS; 6220 Time-of-Flight LC/MS

Revision	Datetime	Status	ChangeLog Entry
0	2016-06-24 03:56:21	ID requested
⏵ 1	2016-07-26 03:12:54	announced

Davis JC, Totten SM, Huang JO, Nagshbandi S, Kirmiz N, Garrido DA, Lewis ZT, Wu LD, Smilowitz JT, German JB, Mills DA, Lebrilla CB, Identification of Oligosaccharides in Feces of Breast-fed Infants and Their Correlation with the Gut Microbial Community. Mol Cell Proteomics, 15(9):2987-3002(2016) [pubmed]

submitter keyword: oligosaccharide, milk, feces, liquid chromatography, mass spectrometry

Carlito B. Lebrilla
contact affiliation	Chemistry Department, University of California, Davis, USA
contact email	cblebrilla@ucdavis.edu
lab head
Jasmine Davis
contact affiliation	University of California, Davis
contact email	jccdavis@ucdavis.edu
dataset submitter

Dataset FTP location NOTE: Most web browsers have now discontinued native support for FTP access within the browser window. But you can usually install another FTP app (we recommend FileZilla) and configure your browser to launch the external application when you click on this FTP link. Or otherwise, launch an app that supports FTP (like FileZilla) and use this address: ftp://ftp.pride.ebi.ac.uk/pride/data/archive/2016/07/PXD004434

PRIDE project URI

• PRIDE
  1. PXD004434
     1. Label: PRIDE project
     2. Name: Human milk oligosaccharides and infant fecal oligosaccharides