PXD004424

PXD004424 is an original dataset announced via ProteomeXchange.

Title	Proteomic and bioinformatic characterization of extracellular vesicles released from human primary macrophages upon influenza A infection
Description	We have previously shown that IAV infection of human monocyte-derived macrophages causes major alterations to subcellular protein trafficking inside the cell and triggers robust protein secretion (Lietzén et al, 2011). Here, we have used high-throughput proteomics to identify proteins secreted in extracellular vesicles (EVs) during influenza A virus infection of human macrophages.
HostingRepository	PRIDE
AnnounceDate	2017-02-07
AnnouncementXML	Submission_2017-02-07_02:25:58.xml
DigitalObjectIdentifier
ReviewLevel	Peer-reviewed dataset
DatasetOrigin	Original dataset
RepositorySupport	Unsupported dataset by repository
PrimarySubmitter	Tuula Nyman
SpeciesList	scientific name: Homo sapiens (Human); NCBI TaxID: 9606;
ModificationList	iodoacetamide derivatized residue
Instrument	Q Exactive

Revision	Datetime	Status	ChangeLog Entry
0	2016-06-23 02:21:45	ID requested
⏵ 1	2017-02-07 02:25:59	announced

Cypryk W, Lorey M, Puustinen A, Nyman TA, Matikainen S, Proteomic and Bioinformatic Characterization of Extracellular Vesicles Released from Human Macrophages upon Influenza A Virus Infection. J Proteome Res, 16(1):217-227(2017) [pubmed]

curator keyword: Biological

submitter keyword: Extracellular vesicle, Influenza A, human primary macrophages, LC-MSMS

Tuula Anneli Nyman
contact affiliation	Institute of Clinical Medicine, Sognsvannsveien 20, Rikshospitalet, 0372 Oslo, Norway Formerly Institute of Biotechnology, University of Helsinki, Finland
contact email	tuula.nyman@helsinki.fi
lab head
Tuula Nyman
contact affiliation	Institute of Biotechnology
contact email	tuula.nyman@helsinki.fi
dataset submitter

Dataset FTP location NOTE: Most web browsers have now discontinued native support for FTP access within the browser window. But you can usually install another FTP app (we recommend FileZilla) and configure your browser to launch the external application when you click on this FTP link. Or otherwise, launch an app that supports FTP (like FileZilla) and use this address: ftp://ftp.pride.ebi.ac.uk/pride/data/archive/2017/02/PXD004424

PRIDE project URI

• PRIDE
  1. PXD004424
     1. Label: PRIDE project
     2. Name: Proteomic and bioinformatic characterization of extracellular vesicles released from human primary macrophages upon influenza A infection