PXD004382
PXD004382 is an original dataset announced via ProteomeXchange.
Dataset Summary
| Title | SRM based analysis of natural genetic variation in C. elegans developmental signalling pathways, 148 proteins |
| Description | Complex traits, including common disease-related traits, are affected by many different genes that function in multiple pathways and networks. Many of the signalling pathways involved in these traits are conserved among species and also present in the nematode C. elegans. To study the effect of natural genetic variation on the abundance of proteins involved in signalling pathways, we used selected reaction monitoring and quantitative trait loci mapping to analyse proteins from four pathways (apoptosis, MAPK, Notch and Wnt) in recombinant inbred lines (RILs) generated from the two genetically divergent C. elegans wild-type strains Bristol N2 and Hawaii CB4856. |
| HostingRepository | PeptideAtlas |
| AnnounceDate | 2016-06-20 |
| AnnouncementXML | Submission_2016-06-20_15:36:35.xml |
| DigitalObjectIdentifier | |
| ReviewLevel | Peer-reviewed dataset |
| DatasetOrigin | Original dataset |
| RepositorySupport | Supported dataset by repository |
| PrimarySubmitter | Kapil Dev Singh |
| SpeciesList | scientific name: Caenorhabditis elegans; NCBI TaxID: 6239; |
| ModificationList | 6x(13)C,4x(15)N labeled L-arginine; 6x(13)C,2x(15)N labeled L-lysine |
| Instrument | TSQ Vantage |
Dataset History
| Revision | Datetime | Status | ChangeLog Entry |
|---|---|---|---|
| 0 | 2016-06-20 14:56:19 | ID requested | |
| ⏵ 1 | 2016-06-20 15:36:36 | announced |
Publication List
| Singh KD, Roschitzki B, Snoek LB, Grossmann J, Zheng X, Elvin M, Kamkina P, Schrimpf SP, Poulin GB, Kammenga JE, Hengartner MO, Natural Genetic Variation Influences Protein Abundances in C. elegans Developmental Signalling Pathways. PLoS One, 11(3):e0149418(2016) [pubmed] |
Keyword List
| curator keyword: selected reaction monitoring, SRM, targeted |
Contact List
| Kapil Dev Singh | |
|---|---|
| contact affiliation | University of Zurich (UZH) |
| contact email | kapil.singh@uzh.ch |
| dataset submitter | |
| Michael O. Hengartner | |
| contact affiliation | University of Zurich (UZH) |
| contact email | michael.hengartner@uzh.ch |
| lab head | |
Full Dataset Link List
| PeptideAtlas dataset URI |
| PASSEL experiment URI |
| PASSEL transition group browser URI |
| PASSEL transition group browser URI |
| PeptideAtlas dataset URI |
| PASSEL transition group browser URI |
| PeptideAtlas dataset URI |
to receive all new ProteomeXchange dataset release announcements!
