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PXD004308

PXD004308 is an original dataset announced via ProteomeXchange.

Dataset Summary
TitleDiffacto quantification-centered large-scale differential analysis
DescriptionIn comparative shotgun proteomics, the objects of measurements are proteolytic peptides, while the objects of interest are proteins. The transition from the measured peptide abundances to the presumed protein expression levels is nontrivial and has not been sufficiently studied. With our new approach named Diffacto, we aim to improve peptide-to-protein transition utilizing the high statistical power of signal correlations in large-scale proteomics datasets. Diffacto detects and removes unreliably measured quantities while aggregating peptide-level information, which makes protein inference and quantification more accurate and robust.
HostingRepositoryMassIVE
AnnounceDate2017-03-16
AnnouncementXMLSubmission_2017-03-16_08:03:39.xml
DigitalObjectIdentifier
ReviewLevelNon peer-reviewed dataset
DatasetOriginOriginal dataset
RepositorySupportUnsupported dataset by repository
PrimarySubmitterBo Zhang
SpeciesList scientific name: Saccharomyces cerevisiae; common name: baker's yeast; NCBI TaxID: 4932; scientific name: Homo sapiens; common name: human; NCBI TaxID: 9606; scientific name: BSA;
ModificationListCarbamidomethyl
InstrumentQ Exactive
Dataset History
RevisionDatetimeStatusChangeLog Entry
02016-06-11 07:37:47ID requested
12017-03-16 08:03:40announced
Publication List
Dataset with its publication pending
Keyword List
submitter keyword: Quantification, Bioinformatics, Covariation
Contact List
Roman Zubarev and Lukas K�ll
lab head
Bo Zhang
contact affiliationKarolinska Institutet
contact emailbo.zhang@ki.se
dataset submitter
Full Dataset Link List
MassIVE dataset URI
Dataset FTP location
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