PXD004191

PXD004191 is an original dataset announced via ProteomeXchange.

Title	Diurnal regulatory landscape of the mouse liver nucleus
Description	To dissect how diurnal rhythms affect key functions such as transcription or chromatin remodelling, we quantified the temporal nuclear accumulation of proteins and phosphoproteins from mouse liver using in vivo stable isotope labelling by amino acids in cell culture (SILAC)-based mass spectrometry (MS). Protein extracts from isotope labelled mice liver nuclei were used as a reference and mixed with extracts from animals collected every 3 h for 45 h total. Phosphopeptide levels were analysed after enrichment with titanium dioxide (TiO2). The proteins levels were also analysed (dataset with project accession PXD003818).
HostingRepository	PRIDE
AnnounceDate	2024-10-22
AnnouncementXML	Submission_2024-10-22_04:23:15.721.xml
DigitalObjectIdentifier
ReviewLevel	Peer-reviewed dataset
DatasetOrigin	Original dataset
RepositorySupport	Unsupported dataset by repository
PrimarySubmitter	Loïc Dayon
SpeciesList	scientific name: Mus musculus (Mouse); NCBI TaxID: 10090;
ModificationList	phosphorylated residue; 6x(13)C labeled residue; acetylated residue; monohydroxylated residue; iodoacetamide derivatized residue
Instrument	LTQ Orbitrap Elite

Revision	Datetime	Status	ChangeLog Entry
0	2016-05-20 00:38:39	ID requested
1	2016-12-22 01:45:22	announced
2	2017-06-20 05:43:18	announced	Updated project metadata.
3	2017-10-24 03:13:41	announced	Updated project metadata.
⏵ 4	2024-10-22 04:23:21	announced	2024-10-22: Updated project metadata.

10.1016/j.cmet.2016.10.003;

Wang J, Mauvoisin D, Martin E, Atger F, Galindo AN, Dayon L, Sizzano F, Palini A, Kussmann M, Waridel P, Quadroni M, Duli, ć V, Naef F, Gachon F, Nuclear Proteomics Uncovers Diurnal Regulatory Landscapes in Mouse Liver. Cell Metab, 25(1):102-117(2017) [pubmed]

curator keyword: Biological

submitter keyword: Phosphoproteomics, LTQ-Orbitrap, Circadian,Liver, SILAC, Nucleus

Frédéric Gachon
contact affiliation	Diabetes and Circadian Rhythms Department, Nestlé Institute of Health Sciences, CH-1015 Lausanne, Switzerland
contact email	frederic.gachon@rd.nestle.com
lab head
Loïc Dayon
contact affiliation	Nestlé Research – Nestlé Institute of Food Safety & Analytical Sciences
contact email	loic.dayon@rd.nestle.com
dataset submitter

Dataset FTP location NOTE: Most web browsers have now discontinued native support for FTP access within the browser window. But you can usually install another FTP app (we recommend FileZilla) and configure your browser to launch the external application when you click on this FTP link. Or otherwise, launch an app that supports FTP (like FileZilla) and use this address: ftp://ftp.pride.ebi.ac.uk/pride/data/archive/2016/12/PXD004191

PRIDE project URI

• PRIDE
  1. PXD004191
     1. Label: PRIDE project
     2. Name: Diurnal regulatory landscape of the mouse liver nucleus