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PXD004144

PXD004144 is an original dataset announced via ProteomeXchange.

Dataset Summary
TitleProteomic analysis of mucus from chronic rhinosinusitis patients with or without nasal polyps
DescriptionPatients with chronic rhinosinusitis (CRS) have abnormal immune responses triggered by a variety of infectious agents, airborne toxins and fungi. Respiratory epithelial cells serve as relay stations capable of amplifying or augmenting cues received from external stimuli to nearby immune cells located in the sinus mucosa. Previous studies have identified increases in complement components and complement gene expression in the mucosa of patients with atopic CRS with nasal polyps (CRSwNP). As part of a larger study, we used shotgun proteomics to quantify changes in mucus proteins between patients with and without nasal polyps.
HostingRepositoryPRIDE
AnnounceDate2016-05-26
AnnouncementXMLSubmission_2016-05-26_05:50:00.xml
DigitalObjectIdentifierhttps://dx.doi.org/10.6019/PXD004144
ReviewLevelPeer-reviewed dataset
DatasetOriginOriginal dataset
RepositorySupportSupported dataset by repository
PrimarySubmitterBenjamin Neely
SpeciesList scientific name: Homo sapiens (Human); NCBI TaxID: 9606;
ModificationListOxidation; Gln->pyro-Glu; Acetyl; Carbamidomethyl; Deamidated
InstrumentLTQ
Dataset History
RevisionDatetimeStatusChangeLog Entry
02016-05-13 02:14:19ID requested
12016-05-26 05:50:01announced
Publication List
Dataset with its publication pending
Keyword List
curator keyword: Biomedical
submitter keyword: human, nasal mucus, mucus, LC-MS/MS
Contact List
Richard R. Drake
contact affiliationDepartment of Cell and Molecular Pharmacology and Experimental Therapeutics, Medical University of South Carolina, Charleston, South Carolina, United States of America
contact emaildraker@musc.edu
lab head
Benjamin Neely
contact affiliationMedical University of South Carolina
contact emailbenaneely@gmail.com
dataset submitter
Full Dataset Link List
Dataset FTP location
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PRIDE project URI
Repository Record List
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