PXD004143

PXD004143 is an original dataset announced via ProteomeXchange.

Title	Allele-Specific Protein Abundance in Human Brain
Description	We describe a method for identifying peptides that result from missense changes and identify peptides among 2 human brains that would have otherwise not been detected. Next, we use this data to estimate of allele-specific protein abundance in human brain for an average per individual, and to estimate apolipoprotein E allele specific abundance in human brain across individuals. Finally, we estimate the heritability of allele-specific protein abundance.
HostingRepository	PRIDE
AnnounceDate	2024-10-22
AnnouncementXML	Submission_2024-10-22_04:29:14.647.xml
DigitalObjectIdentifier
ReviewLevel	Peer-reviewed dataset
DatasetOrigin	Original dataset
RepositorySupport	Unsupported dataset by repository
PrimarySubmitter	Duc Duong
SpeciesList	scientific name: Homo sapiens (Human); NCBI TaxID: 9606;
ModificationList	monohydroxylated residue; iodoacetamide derivatized residue; deamidated residue
Instrument	Q Exactive

Revision	Datetime	Status	ChangeLog Entry
0	2016-05-13 02:06:19	ID requested
1	2017-07-31 03:01:26	announced
⏵ 2	2024-10-22 04:29:22	announced	2024-10-22: Updated project metadata.

10.1021/acs.jproteome.7b00324;

Wingo TS, Duong DM, Zhou M, Dammer EB, Wu H, Cutler DJ, Lah JJ, Levey AI, Seyfried NT, Integrating Next-Generation Genomic Sequencing and Mass Spectrometry To Estimate Allele-Specific Protein Abundance in Human Brain. J Proteome Res, 16(9):3336-3347(2017) [pubmed]

curator keyword: Biological, Biomedical

submitter keyword: Proteogenomics genomics variants proteomics

NIcholas Seyfried
contact affiliation	Emory University
contact email	nseyfri@emory.edu
lab head
Duc Duong
contact affiliation	Center of Neurodegenerative Diseases
contact email	dduong@emory.edu
dataset submitter

Dataset FTP location NOTE: Most web browsers have now discontinued native support for FTP access within the browser window. But you can usually install another FTP app (we recommend FileZilla) and configure your browser to launch the external application when you click on this FTP link. Or otherwise, launch an app that supports FTP (like FileZilla) and use this address: ftp://ftp.pride.ebi.ac.uk/pride/data/archive/2017/07/PXD004143

PRIDE project URI

• PRIDE
  1. PXD004143
     1. Label: PRIDE project
     2. Name: Allele-Specific Protein Abundance in Human Brain