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PXD004097

PXD004097 is an original dataset announced via ProteomeXchange.

Dataset Summary
TitleCanine Flexor Tendon Healing
DescriptionThe project investigated the changes in proteomics profile of canine flexor digitorum profundus tendons 28 days after tendon transection and surgical repair with (ASCs+BMP12) or without a stem cell and growth factor based treatment (repair only). Specifically, adipose-derived mesenchymal stromal cells together with BMP12 were delivered with a polymer scaffold consisting of multiple alternating layers of a heparin/fibrin-based delivery system and a polylactic co-glycolic acid (PLGA) scaffold. Non-operated tendons from contralateral digits were used as normal control (Normal).
HostingRepositoryPRIDE
AnnounceDate2017-06-12
AnnouncementXMLSubmission_2017-06-12_04:49:28.xml
DigitalObjectIdentifierhttps://dx.doi.org/10.6019/PXD004097
ReviewLevelPeer-reviewed dataset
DatasetOriginOriginal dataset
RepositorySupportSupported dataset by repository
PrimarySubmitterHua Shen
SpeciesList scientific name: Canis familiaris (Dog) (Canis lupus familiaris); NCBI TaxID: 9615;
ModificationListOxidation; Carbamidomethyl
InstrumentTripleTOF 5600
Dataset History
RevisionDatetimeStatusChangeLog Entry
02016-05-04 01:36:23ID requested
12017-06-12 04:49:29announced
Publication List
Gelberman RH, Shen H, Kormpakis I, Rothrauff B, Yang G, Tuan RS, Xia Y, Sakiyama-Elbert S, Silva MJ, Thomopoulos S, Effect of adipose-derived stromal cells and BMP12 on intrasynovial tendon repair: A biomechanical, biochemical, and proteomics study. J Orthop Res, 34(4):630-40(2016) [pubmed]
Keyword List
curator keyword: Biological
submitter keyword: Canine, flexor tendon, stem cell, BMP12, TOF LC-MS/MS
Contact List
Richard H Gelberman
contact affiliationWashington University in St. Louis, Department of Orthopaedic Surgery, St. Louis, MO, USA
contact emailgelberman@wudosis.wustl.edu
lab head
Hua Shen
contact affiliationWashington University in St. Louis
contact emailhshen22@wustl.edu
dataset submitter
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Dataset FTP location
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PRIDE project URI
Repository Record List
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