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PXD004075

PXD004075 is an original dataset announced via ProteomeXchange.

Dataset Summary
TitleSpatiotemporal proteomic profiling of cerebral development
DescriptioniPS cell based neuronal differentiation was used to generate pure NPCs and maturing nerons in tissue culture. LFQ mass spectrometry on Q Exactive was used to measure proteomic profile differences between the generated cell types. The identified proteomic signatures were then compared to human fetal cerebral development over the developmental age of 16-36 gestational weeks in four macrodissected regions. Statistical analysis were performed using the Perseus program to compare the datasets and identify spatiotemporally relevant protein modules.
HostingRepositoryPRIDE
AnnounceDate2017-07-14
AnnouncementXMLSubmission_2017-07-14_01:24:29.xml
DigitalObjectIdentifier
ReviewLevelPeer-reviewed dataset
DatasetOriginOriginal dataset
RepositorySupportUnsupported dataset by repository
PrimarySubmitterUgljesa Djuric
SpeciesList scientific name: Homo sapiens (Human); NCBI TaxID: 9606;
ModificationListNo PTMs are included in the dataset
InstrumentQ Exactive
Dataset History
RevisionDatetimeStatusChangeLog Entry
02016-04-29 03:04:24ID requested
12017-07-14 01:24:30announced
Publication List
Djuric U, Rodrigues DC, Batruch I, Ellis J, Shannon P, Diamandis P, Spatiotemporal Proteomic Profiling of Human Cerebral Development. Mol Cell Proteomics, 16(9):1548-1562(2017) [pubmed]
Keyword List
curator keyword: Biological
submitter keyword: LC-MSMS, neuronal differentiation
Contact List
Eleftherios Diamandis
contact affiliationMount Sinai Hospital and University Health Network
contact emailEleftherios.Diamandis@sinaihealthsystem.ca
lab head
Ugljesa Djuric
contact affiliationMt. Sinai Hospital
contact emailugljesa.djuric@mail.utoronto.ca
dataset submitter
Full Dataset Link List
Dataset FTP location
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PRIDE project URI
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