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PXD003981

PXD003981 is an original dataset announced via ProteomeXchange.

Dataset Summary
TitleData in support of Synthesis and deposition of basement membrane proteins by primary brain capillary endothelial cells in a murine model of the blood-brain barrier
DescriptionThe aim of the present study was to analyze four different in vitro models of the murine BBB for expression and possible secretion of major basement membrane proteins from murine BCECs (mBCECs). The mBCECs and pericytes were isolated from brains of adult C57BL/6 mice, and glial cells (mainly astrocytes and microglia) were prepared from cerebral cortices of newborn C57BL/6 mice. The mBCECs were grown as mono-culture, in co-culture with pericytes or mixed glial cells, or as a triple-culture with both pericytes and mixed glial cells.
HostingRepositoryPRIDE
AnnounceDate2024-10-22
AnnouncementXMLSubmission_2024-10-22_03:58:55.695.xml
DigitalObjectIdentifier
ReviewLevelPeer-reviewed dataset
DatasetOriginOriginal dataset
RepositorySupportUnsupported dataset by repository
PrimarySubmitterAllan Stensballe
SpeciesList scientific name: Mus musculus (Mouse); NCBI TaxID: 10090;
ModificationListiodoacetamide derivatized residue
InstrumentQ Exactive
Dataset History
RevisionDatetimeStatusChangeLog Entry
02016-04-18 05:48:04ID requested
12016-08-03 03:22:32announced
22024-10-22 03:59:00announced2024-10-22: Updated project metadata.
Publication List
10.1111/jnc.13747;
Thomsen MS, Birkelund S, Burkhart A, Stensballe A, Moos T, Synthesis and deposition of basement membrane proteins by primary brain capillary endothelial cells in a murine model of the blood-brain barrier. J Neurochem, 140(5):741-754(2017) [pubmed]
Keyword List
curator keyword: Biological
submitter keyword: Blood-brain barrier
primary murine capillary endothelial cells
basement membrane
in vitro models
Contact List
Allan Stensballe
contact affiliationAalborg University Fredrik Bajersvej 3B 9220 Aalborg
contact emailas@hst.aau.dk
lab head
Allan Stensballe
contact affiliationAalborg University
contact emailas@hst.aau.dk
dataset submitter
Full Dataset Link List
Dataset FTP location
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PRIDE project URI
Repository Record List
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