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PXD003818

PXD003818 is an original dataset announced via ProteomeXchange.

Dataset Summary
TitleDiurnal regulatory landscape of the mouse liver nucleus
DescriptionTo dissect how diurnal rhythms affect key functions such as transcription or chromatin remodeling, we quantified the temporal nuclear accumulation of proteins and phosphoproteins from mouse liver by SILAC-based MS. Protein extracts from isotope labelled mice liver nuclei were used as a reference and mixed with extracts from animals collected every 3h for 45h total. Total protein levels were analysed together with phosphopeptides after enrichment (see separate dataset for phospho data).
HostingRepositoryPRIDE
AnnounceDate2017-10-24
AnnouncementXMLSubmission_2017-10-24_02:15:43.xml
DigitalObjectIdentifier
ReviewLevelPeer-reviewed dataset
DatasetOriginOriginal dataset
RepositorySupportUnsupported dataset by repository
PrimarySubmitterManfredo Quadroni
SpeciesList scientific name: Mus musculus (Mouse); NCBI TaxID: 10090;
ModificationList6x(13)C labeled residue; monohydroxylated residue; iodoacetamide derivatized residue
InstrumentLTQ Orbitrap Velos
Dataset History
RevisionDatetimeStatusChangeLog Entry
02016-03-18 08:00:03ID requested
12016-12-13 00:53:03announced
22017-10-24 02:15:44announcedUpdated project metadata.
Publication List
Wang J, Mauvoisin D, Martin E, Atger F, Galindo AN, Dayon L, Sizzano F, Palini A, Kussmann M, Waridel P, Quadroni M, Dulić V, Naef F, Gachon F, Nuclear Proteomics Uncovers Diurnal Regulatory Landscapes in Mouse Liver. Cell Metab, 25(1):102-117(2017) [pubmed]
Keyword List
curator keyword: Biological
submitter keyword: liver, nucleus, circadian rythms, mouse, orbitrap
Contact List
Frederic Gachon
contact affiliationDiabetes and Circadian Rhythms Department, Nestlé Institute of Health Sciences, CH-1015 Lausanne, Switzerland
contact emailFrederic.Gachon@rd.nestle.com
lab head
Manfredo Quadroni
contact affiliationUniversity of Lausanne
contact emailmanfredo.quadroni@unil.ch
dataset submitter
Full Dataset Link List
Dataset FTP location
PRIDE project URI
Repository Record List
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