PXD003818

PXD003818 is an original dataset announced via ProteomeXchange.

Title	Diurnal regulatory landscape of the mouse liver nucleus
Description	To dissect how diurnal rhythms affect key functions such as transcription or chromatin remodeling, we quantified the temporal nuclear accumulation of proteins and phosphoproteins from mouse liver by SILAC-based MS. Protein extracts from isotope labelled mice liver nuclei were used as a reference and mixed with extracts from animals collected every 3h for 45h total. Total protein levels were analysed together with phosphopeptides after enrichment (see separate dataset for phospho data).
HostingRepository	PRIDE
AnnounceDate	2017-10-24
AnnouncementXML	Submission_2017-10-24_02:15:43.xml
DigitalObjectIdentifier
ReviewLevel	Peer-reviewed dataset
DatasetOrigin	Original dataset
RepositorySupport	Unsupported dataset by repository
PrimarySubmitter	Manfredo Quadroni
SpeciesList	scientific name: Mus musculus (Mouse); NCBI TaxID: 10090;
ModificationList	6x(13)C labeled residue; monohydroxylated residue; iodoacetamide derivatized residue
Instrument	LTQ Orbitrap Velos

Revision	Datetime	Status	ChangeLog Entry
0	2016-03-18 08:00:03	ID requested
1	2016-12-13 00:53:03	announced
⏵ 2	2017-10-24 02:15:44	announced	Updated project metadata.

Wang J, Mauvoisin D, Martin E, Atger F, Galindo AN, Dayon L, Sizzano F, Palini A, Kussmann M, Waridel P, Quadroni M, Dulić V, Naef F, Gachon F, Nuclear Proteomics Uncovers Diurnal Regulatory Landscapes in Mouse Liver. Cell Metab, 25(1):102-117(2017) [pubmed]

curator keyword: Biological

submitter keyword: liver, nucleus, circadian rythms, mouse, orbitrap

Frederic Gachon
contact affiliation	Diabetes and Circadian Rhythms Department, Nestlé Institute of Health Sciences, CH-1015 Lausanne, Switzerland
contact email	Frederic.Gachon@rd.nestle.com
lab head
Manfredo Quadroni
contact affiliation	University of Lausanne
contact email	manfredo.quadroni@unil.ch
dataset submitter

Dataset FTP location

PRIDE project URI

• PRIDE
  1. PXD003818
     1. Label: PRIDE project
     2. Name: Diurnal regulatory landscape of the mouse liver nucleus