Project describe: The P. falciparum export 300-400 proteins during infect human red blood cell, where they are involved in host cell modification including We recently identified a novel structure in P. falciparum-infected erythrocytes which we refer to as J-dots. These structures contain exported parasite-encoded Hsp40s and are implicated in protein transport through the erythrocyte. This project wants isolation and proteomic characterisation of parasite-induced intra-erythrocytic structure to understand their importance in parasite survival and virulence. A more thorough understanding of this novel process may eventually lead to new avenues for therapy.