PXD003789

PXD003789 is an original dataset announced via ProteomeXchange.

Title	Proteomic analysis of exported chaperone/co－chaperone complexes of P. falciparum reveals an array of complex protein-protein interactions
Description	Project describe: The P. falciparum export 300-400 proteins during infect human red blood cell, where they are involved in host cell modification including We recently identified a novel structure in P. falciparum-infected erythrocytes which we refer to as J-dots. These structures contain exported parasite-encoded Hsp40s and are implicated in protein transport through the erythrocyte. This project wants isolation and proteomic characterisation of parasite-induced intra-erythrocytic structure to understand their importance in parasite survival and virulence. A more thorough understanding of this novel process may eventually lead to new avenues for therapy.
HostingRepository	PRIDE
AnnounceDate	2018-10-18
AnnouncementXML	Submission_2018-10-17_18:45:54.xml
DigitalObjectIdentifier
ReviewLevel	Peer-reviewed dataset
DatasetOrigin	Original dataset
RepositorySupport	Unsupported dataset by repository
PrimarySubmitter	Qi Zhang
SpeciesList	scientific name: Plasmodium falciparum; NCBI TaxID: 5833; scientific name: Homo sapiens (Human); NCBI TaxID: 9606;
ModificationList	No PTMs are included in the dataset
Instrument	LTQ Orbitrap Elite

Revision	Datetime	Status	ChangeLog Entry
0	2016-03-15 02:31:36	ID requested
⏵ 1	2018-10-17 18:45:56	announced

Zhang Q, Ma C, Oberli A, Zinz A, Engels S, Przyborski JM, Proteomic analysis of exported chaperone/co-chaperone complexes of P. falciparum reveals an array of complex protein-protein interactions. Sci Rep, 7():42188(2017) [pubmed]

curator keyword: Biomedical

submitter keyword: red blood cell , P. falciparum, co-ip, J-dots, LC-MS/MS

Jude M. Przyborski
contact affiliation	Parasitologie FB Biology University of Marburg
contact email	przybors@staff.uni-marburg.de
lab head
Qi Zhang
contact affiliation	Philipp University of Marburg
contact email	zhangqi4@staff.uni-marburg.de
dataset submitter

Dataset FTP location NOTE: Most web browsers have now discontinued native support for FTP access within the browser window. But you can usually install another FTP app (we recommend FileZilla) and configure your browser to launch the external application when you click on this FTP link. Or otherwise, launch an app that supports FTP (like FileZilla) and use this address: ftp://ftp.pride.ebi.ac.uk/pride/data/archive/2018/10/PXD003789

PRIDE project URI

• PRIDE
  1. PXD003789
     1. Label: PRIDE project
     2. Name: Proteomic analysis of exported chaperone/co－chaperone complexes of P. falciparum reveals an array of complex protein-protein interactions