PXD003649

PXD003649 is an original dataset announced via ProteomeXchange.

Dataset Summary

Title	Bacterial Interactomes: Desulfovibrio vulgaris_TAP_part 2_LTQ Data
Description	Here we present an AP-MS survey of the bacterium Desulfovibrio vulgaris. We have identified 459 high confidence PPIs from D. vulgaris. Compared to the nine published interactomes, our two networks are smaller; are much less highly connected; have significantly lower false discovery rates; and are much more enriched in protein pairs that are encoded in the same operon, have similar functions, and are reproducibly detected in other physical interaction assays. Our work establishes more stringent benchmarks for the properties of protein interactomes and suggests that bona fide PPIs much more frequently involve protein partners that are annotated with similar functions or that can be validated in independent assays than earlier studies suggested.
HostingRepository	MassIVE
AnnounceDate	2016-02-16
AnnouncementXML	Submission_2016-02-16_09:43:52.xml
DigitalObjectIdentifier
ReviewLevel	Non peer-reviewed dataset
DatasetOrigin	Original dataset
RepositorySupport	Unsupported dataset by repository
PrimarySubmitter	Witkowska
SpeciesList	scientific name: Desulfovibrio vulgaris str. Hildenborough; NCBI TaxID: 882;
ModificationList	No PTMs are included in the dataset
Instrument	LTQ XL

Dataset History

Revision	Datetime	Status	ChangeLog Entry
0	2016-02-16 09:43:16	ID requested
⏵ 1	2016-02-16 09:43:52	announced

Publication List

Dataset with its publication pending

Dataset with its publication pending

Keyword List

submitter keyword: protein-protein interactions, AP-MS, tandem affinity purification, Desulfovibrio vulgaris

submitter keyword: protein-protein interactions, AP-MS, tandem affinity purification, Desulfovibrio vulgaris

Contact List

Gareth Butland
lab head
Witkowska
contact affiliation	UCSF
contact email	h_ewa_witkowska@yahoo.com
dataset submitter

Full Dataset Link List

MassIVE dataset URI
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MassIVE dataset URI

Dataset FTP location
NOTE: Most web browsers have now discontinued native support for FTP access within the browser window. But you can usually install another FTP app (we recommend FileZilla) and configure your browser to launch the external application when you click on this FTP link. Or otherwise, launch an app that supports FTP (like FileZilla) and use this address: ftp://massive.ucsd.edu/MSV000079277