PXD003556

PXD003556 is an original dataset announced via ProteomeXchange.

Title	The proteomes of plasmodium falciparum mature male and female gametocytes
Description	Gametocytes are obligate for the transmission of malaria parasite to mosquito. This study reports the first comprehensive proteomes of accurately separated mature male and female Plasmodium falciparum gametocytes using a transgenic line. the proteomes revealed significant differences that are consistent with the divergent functions of the two sexes. While the male proteome is enriched in proteins associated with flagella and genome replication, the female proteome is more abundant in proteins involved in metabolism, translation and organellar functions.
HostingRepository	PRIDE
AnnounceDate	2017-01-30
AnnouncementXML	Submission_2017-01-30_11:14:57.xml
DigitalObjectIdentifier	https://dx.doi.org/10.6019/PXD003556
ReviewLevel	Peer-reviewed dataset
DatasetOrigin	Original dataset
RepositorySupport	Supported dataset by repository
PrimarySubmitter	JUN MIAO
SpeciesList	scientific name: Plasmodium falciparum (isolate 3D7); NCBI TaxID: 36329;
ModificationList	Deamidated; Oxidation; Acetyl; Carbamidomethyl; Gln->pyro-Glu
Instrument	Q Exactive

Revision	Datetime	Status	ChangeLog Entry
0	2016-02-01 08:48:30	ID requested
⏵ 1	2017-01-30 11:14:58	announced

Miao J, Chen Z, Wang Z, Shrestha S, Li X, Li R, Cui L, Sex-Specific Biology of the Human Malaria Parasite Revealed from the Proteomes of Mature Male and Female Gametocytes. Mol Cell Proteomics, 16(4):537-551(2017) [pubmed]

curator keyword: Biomedical

submitter keyword: Plasmodium falciparum, gametocyte, sex-specific, proteome

Liwang Cui
contact affiliation	Department of Entomology, Pennsylvania State University, USA
contact email	luc2@psu.edu
lab head
JUN MIAO
contact affiliation	Pennsylvania State University
contact email	jum23@psu.edu
dataset submitter

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PRIDE project URI

• PRIDE
  1. PXD003556
     1. Label: PRIDE project
     2. Name: The proteomes of plasmodium falciparum mature male and female gametocytes