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PXD003556

PXD003556 is an original dataset announced via ProteomeXchange.

Dataset Summary
TitleThe proteomes of plasmodium falciparum mature male and female gametocytes
DescriptionGametocytes are obligate for the transmission of malaria parasite to mosquito. This study reports the first comprehensive proteomes of accurately separated mature male and female Plasmodium falciparum gametocytes using a transgenic line. the proteomes revealed significant differences that are consistent with the divergent functions of the two sexes. While the male proteome is enriched in proteins associated with flagella and genome replication, the female proteome is more abundant in proteins involved in metabolism, translation and organellar functions.
HostingRepositoryPRIDE
AnnounceDate2017-01-30
AnnouncementXMLSubmission_2017-01-30_11:14:57.xml
DigitalObjectIdentifierhttps://dx.doi.org/10.6019/PXD003556
ReviewLevelPeer-reviewed dataset
DatasetOriginOriginal dataset
RepositorySupportSupported dataset by repository
PrimarySubmitterJUN MIAO
SpeciesList scientific name: Plasmodium falciparum (isolate 3D7); NCBI TaxID: 36329;
ModificationListDeamidated; Oxidation; Acetyl; Carbamidomethyl; Gln->pyro-Glu
InstrumentQ Exactive
Dataset History
RevisionDatetimeStatusChangeLog Entry
02016-02-01 08:48:30ID requested
12017-01-30 11:14:58announced
Publication List
Miao J, Chen Z, Wang Z, Shrestha S, Li X, Li R, Cui L, Sex-Specific Biology of the Human Malaria Parasite Revealed from the Proteomes of Mature Male and Female Gametocytes. Mol Cell Proteomics, 16(4):537-551(2017) [pubmed]
Keyword List
curator keyword: Biomedical
submitter keyword: Plasmodium falciparum, gametocyte, sex-specific, proteome
Contact List
Liwang Cui
contact affiliationDepartment of Entomology, Pennsylvania State University, USA
contact emailluc2@psu.edu
lab head
JUN MIAO
contact affiliationPennsylvania State University
contact emailjum23@psu.edu
dataset submitter
Full Dataset Link List
Dataset FTP location
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PRIDE project URI
Repository Record List
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