PXD003554

PXD003554 is an original dataset announced via ProteomeXchange.

Title	Nuclear nucleolin interactome analysis
Description	Nucleolin (NCL) is a major component of the cell nucleolus, which has the ability to rapidly shuttle to several other cell’s compartments. NCL has been shown to play important roles in a variety of essential functions among which ribosome biogenesis, gene expression and cell growth. However, the precise mechanisms underlying NCL functions are still unclear. Our study aimed to provide new information on NCL functions via the identification of its nuclear interacting partners. Using an interactomics approach, we identified 140 binding partners of NCL, among which, a 100 of them, were specifically found associated to NCL independently of the presence of RNA.
HostingRepository	PRIDE
AnnounceDate	2016-04-11
AnnouncementXML	Submission_2016-04-11_02:29:51.xml
DigitalObjectIdentifier
ReviewLevel	Peer-reviewed dataset
DatasetOrigin	Original dataset
RepositorySupport	Unsupported dataset by repository
PrimarySubmitter	Yohann Couté
SpeciesList	scientific name: Homo sapiens (Human); NCBI TaxID: 9606;
ModificationList	monohydroxylated residue; acetylated residue; iodoacetamide derivatized residue
Instrument	LTQ Orbitrap Velos

Revision	Datetime	Status	ChangeLog Entry
0	2016-02-01 05:48:39	ID requested
⏵ 1	2016-04-11 02:29:52	announced

Salvetti A, Cout, é Y, Epstein A, Arata L, Kraut A, Navratil V, Bouvet P, Greco A, Nuclear Functions of Nucleolin through Global Proteomics and Interactomic Approaches. J Proteome Res, 15(5):1659-69(2016) [pubmed]

curator keyword: Biological

submitter keyword: Nucleolin, tandem affinity purification, nanoLC-MS/MS

Christophe Bruley
contact affiliation	EDyP lab
contact email	christophe.bruley@cea.fr
lab head
Yohann Couté
contact affiliation	Laboratoire d'Etude de la Dynamique des Protéomes
contact email	yohann.coute@cea.fr
dataset submitter

Dataset FTP location NOTE: Most web browsers have now discontinued native support for FTP access within the browser window. But you can usually install another FTP app (we recommend FileZilla) and configure your browser to launch the external application when you click on this FTP link. Or otherwise, launch an app that supports FTP (like FileZilla) and use this address: ftp://ftp.pride.ebi.ac.uk/pride/data/archive/2016/04/PXD003554

PRIDE project URI

• PRIDE
  1. PXD003554
     1. Label: PRIDE project
     2. Name: Nuclear nucleolin interactome analysis