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PXD003517

PXD003517 is an original dataset announced via ProteomeXchange.

Dataset Summary
TitleECM-enriched mouse lung - TMT-based quantitative mass spectrometry analysis was performed on ECM-enriched preparation from normal murine lung, bleomycin-induced fibrotic lung, primary tumors and lymph node metastasis isolated from the KrasG12D/+p53-/- mouse model of lung adenocarcinoma. Three independent samples were processed and analyzed for each condition. This study identified ECM signatures of normal and diseased lung tissue.
DescriptionTMT-based quantitative mass spectrometry analysis was performed on ECM-enriched preparation from normal murine lung, bleomycin-induced fibrotic lung, primary tumors and lymph node metastasis isolated from the KrasG12D/+p53-/- mouse model of lung adenocarcinoma. Three independent samples were processed and analyzed for each condition. This study identified ECM signatures of normal and diseased lung tissue.
HostingRepositoryPRIDE
AnnounceDate2020-03-12
AnnouncementXMLSubmission_2020-03-12_03:39:20.xml
DigitalObjectIdentifierhttps://dx.doi.org/10.6019/PXD003517
ReviewLevelPeer-reviewed dataset
DatasetOriginOriginal dataset
RepositorySupportSupported dataset by repository
PrimarySubmitterAmanda Del Rosario
SpeciesList scientific name: Mus musculus (Mouse); NCBI TaxID: 10090;
ModificationListTMT6plex-126 reporter+balance reagent acylated residue; carbamoylated residue; phosphorylated residue; deaminated residue; monohydroxylated residue; iodoacetamide derivatized residue; deamidated residue
InstrumentQ Exactive
Dataset History
RevisionDatetimeStatusChangeLog Entry
02016-01-25 02:08:16ID requested
12017-06-21 03:57:51announced
22020-03-12 03:39:21announced2020-03-12: Updated project metadata.
Publication List
Dataset with its publication pending
Keyword List
curator keyword: Biomedical
submitter keyword: extraceullar matrix
Contact List
Amanda Del Rosario
contact affiliationMIT Koch Institute
contact emailaweaver@mit.edu
lab head
Amanda Del Rosario
contact affiliationJanssen Pharmaceuticals
contact emailadelros1@its.jnj.com
dataset submitter
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Dataset FTP location
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PRIDE project URI
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