PXD003517 is an
original dataset announced via ProteomeXchange.
Dataset Summary
Title | ECM-enriched mouse lung - TMT-based quantitative mass spectrometry analysis was performed on ECM-enriched preparation from normal murine lung, bleomycin-induced fibrotic lung, primary tumors and lymph node metastasis isolated from the KrasG12D/+p53-/- mouse model of lung adenocarcinoma. Three independent samples were processed and analyzed for each condition. This study identified ECM signatures of normal and diseased lung tissue. |
Description | TMT-based quantitative mass spectrometry analysis was performed on ECM-enriched preparation from normal murine lung, bleomycin-induced fibrotic lung, primary tumors and lymph node metastasis isolated from the KrasG12D/+p53-/- mouse model of lung adenocarcinoma. Three independent samples were processed and analyzed for each condition. This study identified ECM signatures of normal and diseased lung tissue. |
HostingRepository | PRIDE |
AnnounceDate | 2020-03-12 |
AnnouncementXML | Submission_2020-03-12_03:39:20.xml |
DigitalObjectIdentifier | https://dx.doi.org/10.6019/PXD003517 |
ReviewLevel | Peer-reviewed dataset |
DatasetOrigin | Original dataset |
RepositorySupport | Supported dataset by repository |
PrimarySubmitter | Amanda Del Rosario |
SpeciesList | scientific name: Mus musculus (Mouse); NCBI TaxID: 10090; |
ModificationList | TMT6plex-126 reporter+balance reagent acylated residue; carbamoylated residue; phosphorylated residue; deaminated residue; monohydroxylated residue; iodoacetamide derivatized residue; deamidated residue |
Instrument | Q Exactive |
Dataset History
Revision | Datetime | Status | ChangeLog Entry |
0 | 2016-01-25 02:08:16 | ID requested | |
1 | 2017-06-21 03:57:51 | announced | |
⏵ 2 | 2020-03-12 03:39:21 | announced | 2020-03-12: Updated project metadata. |
Publication List
Dataset with its publication pending |
Keyword List
curator keyword: Biomedical |
submitter keyword: extraceullar matrix |
Contact List
Amanda Del Rosario |
contact affiliation | MIT Koch Institute |
contact email | aweaver@mit.edu |
lab head | |
Amanda Del Rosario |
contact affiliation | Janssen Pharmaceuticals |
contact email | adelros1@its.jnj.com |
dataset submitter | |
Full Dataset Link List
Dataset FTP location
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PRIDE project URI |
Repository Record List
[ + ]
[ - ]
- PRIDE
- PXD003517
- Label: PRIDE project
- Name: ECM-enriched mouse lung - TMT-based quantitative mass spectrometry analysis was performed on ECM-enriched preparation from normal murine lung, bleomycin-induced fibrotic lung, primary tumors and lymph node metastasis isolated from the KrasG12D/+p53-/- mouse model of lung adenocarcinoma. Three independent samples were processed and analyzed for each condition. This study identified ECM signatures of normal and diseased lung tissue.