PXD003425

PXD003425 is an original dataset announced via ProteomeXchange.

Title	Modified fish diet in six dolphins
Description	Feeding a modified fish diet has been suggested to improve insulin sensitivity in bottlenose dolphins; however insulin sensitivity was not directly measured. Since demonstrating an improvement in insulin sensitivity is technically difficult in dolphins, we postulated that directional changes in the hormone axis: fibroblast growth factor 21 (FGF21)/Adiponectin/Ceramide (Cer), could provide further support to this hypothesis. Proteomic analysis of the serum proteins revealed few changes in serum proteins over the study period. In conclusion, changing the types of fish fed to dolphins resulted in increases in the insulin sensitizing hormone adiponectin and serum sphingosines consistent with an insulin sensitizing phenotype.
HostingRepository	PRIDE
AnnounceDate	2023-11-14
AnnouncementXML	Submission_2023-11-14_08:48:53.278.xml
DigitalObjectIdentifier	https://dx.doi.org/10.6019/PXD003425
ReviewLevel	Peer-reviewed dataset
DatasetOrigin	Original dataset
RepositorySupport	Supported dataset by repository
PrimarySubmitter	Philip Sobolesky
SpeciesList	scientific name: Tursiops truncatus (Atlantic bottle-nosed dolphin) (Delphinus truncatus); NCBI TaxID: 9739;
ModificationList	Oxidation; Carbamidomethyl; Gln->pyro-Glu
Instrument	TripleTOF 5600

Revision	Datetime	Status	ChangeLog Entry
0	2016-01-06 01:45:51	ID requested
1	2016-04-20 09:45:41	announced
⏵ 2	2023-11-14 08:48:53	announced	2023-11-14: Updated project metadata.

10.6019/PXD003425;

curator keyword: Biological

submitter keyword: Heptadecanoic acid, Dolphins,Adiponectin

Michael G. Janech
contact affiliation	Division of Nephrology, Department of Medicine, Medical University of South Carolina
contact email	janechmg@musc.edu
lab head
Philip Sobolesky
contact affiliation	Medical University of South Carolina
contact email	psobolesky@gmail.com
dataset submitter

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PRIDE project URI

• PRIDE
  1. PXD003425
     1. Label: PRIDE project
     2. Name: Modified fish diet in six dolphins