PXD003395

PXD003395 is an original dataset announced via ProteomeXchange.

Title	The proteomics of dormancy: lessons from encysted hydrated embryos of an aquatic invertebrate
Description	Dormancy is displayed by several organisms when environmental conditions cannot support their regular life activities. Numerous aquatic invertebrates survive for decades in a hydrated state as encysted embryos. In search for functional pathways that are associated with this form of dormancy, we used label-free quantitative proteome profiling and compared the proteomes of encysted dormant embryos (“resting eggs”; RE) with non-dormant embryos (amictic eggs; AM) of the rotifer Brachionus plicatilis. We also compared resting eggs (RE) before and after an obligatory dormant period (E0). A total of 2,631 proteins were identified in AM, RE and E0 eggs. Significantly lower numbers of proteins were determined for RE and E0, compared with AM. About 80% of the proteins were upregulated in AM, in the comparisons of AM vs. RE and AM vs. E0. The differentially expressed proteins were assigned to a large number of putative functional pathways, demonstrating the dramatic changes occurring during dormancy.
HostingRepository	PRIDE
AnnounceDate	2017-07-25
AnnouncementXML	Submission_2017-07-25_04:04:34.xml
DigitalObjectIdentifier
ReviewLevel	Peer-reviewed dataset
DatasetOrigin	Original dataset
RepositorySupport	Unsupported dataset by repository
PrimarySubmitter	Tamar Ziv
SpeciesList	scientific name: Brachionus plicatilis (Marine rotifer) (Brachionus muelleri); NCBI TaxID: 10195;
ModificationList	No PTMs are included in the dataset
Instrument	Q Exactive

Revision	Datetime	Status	ChangeLog Entry
0	2016-01-04 01:13:46	ID requested
⏵ 1	2017-07-25 04:04:36	announced

Ziv T, Chalifa-Caspi V, Denekamp N, Plaschkes I, Kierszniowska S, Blais I, Admon A, Lubzens E, Dormancy in Embryos: Insight from Hydrated Encysted Embryos of an Aquatic Invertebrate. Mol Cell Proteomics, 16(10):1746-1769(2017) [pubmed]

curator keyword: Biological

submitter keyword: resting eggs,rotifers, dormancy

Esther Lubzens
contact affiliation	Faculty of Biology, Technion-Israel Institute of Technology, Haifa, Israel
contact email	elubzens@tx.technion.ac.ik
lab head
Tamar Ziv
contact affiliation	Technion
contact email	tamarz@tx.technion.ac.il
dataset submitter

Dataset FTP location NOTE: Most web browsers have now discontinued native support for FTP access within the browser window. But you can usually install another FTP app (we recommend FileZilla) and configure your browser to launch the external application when you click on this FTP link. Or otherwise, launch an app that supports FTP (like FileZilla) and use this address: ftp://ftp.pride.ebi.ac.uk/pride/data/archive/2017/07/PXD003395

PRIDE project URI

• PRIDE
  1. PXD003395
     1. Label: PRIDE project
     2. Name: The proteomics of dormancy: lessons from encysted hydrated embryos of an aquatic invertebrate