PXD003382 is an
original dataset announced via ProteomeXchange.
Dataset Summary
Title | CEP215_gallus_interactome |
Description | To establish the molecular basis for CEP215 function in centrosome-spindle pole attachment, we employed an unbiased proteomic approach to isolat e and identify CEP215 interactors. To this end, affinity purification tags ( Gs TAP containing protein G and streptavidin-binding protein) were inserted in-frame into both alleles of the CEP215 gene (CEP215-TAP cell line) in the chicken B cell line, DT40. Following affinity purification, protein complexes were analysed by mass spectr ometry |
HostingRepository | PRIDE |
AnnounceDate | 2016-03-31 |
AnnouncementXML | Submission_2016-03-31_07:04:08.xml |
DigitalObjectIdentifier | |
ReviewLevel | Peer-reviewed dataset |
DatasetOrigin | Original dataset |
RepositorySupport | Unsupported dataset by repository |
PrimarySubmitter | Pavithra Lakshminarasimhan |
SpeciesList | scientific name: Gallus gallus (Chicken); NCBI TaxID: 9031; |
ModificationList | monohydroxylated residue; deamidated residue |
Instrument | LTQ Orbitrap Velos |
Dataset History
Revision | Datetime | Status | ChangeLog Entry |
0 | 2015-12-21 05:52:57 | ID requested | |
⏵ 1 | 2016-03-31 07:04:09 | announced | |
Publication List
Chavali PL, Chandrasekaran G, Barr AR, T, รก, trai P, Taylor C, Papachristou EK, Woods CG, Chavali S, Gergely F, A CEP215-HSET complex links centrosomes with spindle poles and drives centrosome clustering in cancer. Nat Commun, 7():11005(2016) [pubmed] |
Keyword List
curator keyword: Biological |
submitter keyword: mitosis, centrosome, centrosome clustering, cancer, micr ocephaly, CEP215, HSET, |
Contact List
Fanni gergely |
contact affiliation | Cancer Research UK Cambridge Institute, Li Ka Shing Centre , University of Cambridge, Robinson Way, Cambridge CB2 0RE, UK |
contact email | fanni.gergely@cruk.cam.ac.uk |
lab head | |
Pavithra Lakshminarasimhan |
contact affiliation | University of cambridge |
contact email | pavithra.lakshminarasimhan@cruk.cam.ac.uk |
dataset submitter | |
Full Dataset Link List
Dataset FTP location
NOTE: Most web browsers have now discontinued native support for FTP access within the browser window. But you can usually install another FTP app (we recommend FileZilla) and configure your browser to launch the external application when you click on this FTP link. Or otherwise, launch an app that supports FTP (like FileZilla) and use this address: ftp://ftp.pride.ebi.ac.uk/pride/data/archive/2016/03/PXD003382 |
PRIDE project URI |
Repository Record List
[ + ]
[ - ]
- PRIDE
- PXD003382
- Label: PRIDE project
- Name: CEP215_gallus_interactome