PXD003379

PXD003379 is an original dataset announced via ProteomeXchange.

Dataset Summary

Title	Inner ear proteomics/transcriptomics
Description	The correlation between expression levels of mRNA and protein in mammals is relatively low, with a Pearson correlation coefficient of ~0.40. Post transcriptional regulation contributes to this low correlation. Across taxa, it was demonstrated that translation efficiency, i.e. the protein-to-mRNA ratio in steady state, varies between species in a direction that buffers the protein levels from changes in the transcript abundance. Evidence for this behavior in tissues is sparse. We asked whether this phenomenon is evident in our auditory system data, and on previously obtained proteomic and transcriptomic data from different tissue datasets.
HostingRepository	PRIDE
AnnounceDate	2024-10-22
AnnouncementXML	Submission_2024-10-22_04:27:38.849.xml
DigitalObjectIdentifier
ReviewLevel	Peer-reviewed dataset
DatasetOrigin	Original dataset
RepositorySupport	Unsupported dataset by repository
PrimarySubmitter	Yair Pozniak
SpeciesList	scientific name: Mus musculus (Mouse); NCBI TaxID: 10090;
ModificationList	No PTMs are included in the dataset
Instrument	Q Exactive

Dataset History

Revision	Datetime	Status	ChangeLog Entry
0	2015-12-21 01:52:26	ID requested
1	2017-04-24 00:15:31	announced
⏵ 2	2024-10-22 04:27:47	announced	2024-10-22: Updated project metadata.

Publication List

10.1186/s12864-017-3683-9;
Perl K, Ushakov K, Pozniak Y, Yizhar-Barnea O, Bhonker Y, Shivatzki S, Geiger T, Avraham KB, Shamir R, Reduced changes in protein compared to mRNA levels across non-proliferating tissues. BMC Genomics, 18(1):305(2017) [pubmed]

10.1186/s12864-017-3683-9;

Perl K, Ushakov K, Pozniak Y, Yizhar-Barnea O, Bhonker Y, Shivatzki S, Geiger T, Avraham KB, Shamir R, Reduced changes in protein compared to mRNA levels across non-proliferating tissues. BMC Genomics, 18(1):305(2017) [pubmed]

Keyword List

curator keyword: Biological
submitter keyword: vestibule,ear, protein, correlation, cochlea, mrna

curator keyword: Biological

submitter keyword: vestibule,ear, protein, correlation, cochlea, mrna

Contact List

Tamar Geiger
contact affiliation	Department of Humand Molecular Genetics and Biochemistry, Tel Aviv University, Tel Aviv, Israel
contact email	geiger@tauex.tau.ac.il
lab head
Yair Pozniak
contact affiliation	Tel Aviv University
contact email	yair.poz@gmail.com
dataset submitter

Full Dataset Link List

Dataset FTP location NOTE: Most web browsers have now discontinued native support for FTP access within the browser window. But you can usually install another FTP app (we recommend FileZilla) and configure your browser to launch the external application when you click on this FTP link. Or otherwise, launch an app that supports FTP (like FileZilla) and use this address: ftp://ftp.pride.ebi.ac.uk/pride/data/archive/2017/04/PXD003379
PRIDE project URI

Dataset FTP location
NOTE: Most web browsers have now discontinued native support for FTP access within the browser window. But you can usually install another FTP app (we recommend FileZilla) and configure your browser to launch the external application when you click on this FTP link. Or otherwise, launch an app that supports FTP (like FileZilla) and use this address: ftp://ftp.pride.ebi.ac.uk/pride/data/archive/2017/04/PXD003379

PRIDE project URI

Repository Record List

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