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PXD003337

PXD003337 is an original dataset announced via ProteomeXchange.

Dataset Summary
TitleLongitudinal quantification of the GCF proteome during progression from gingivitis to periodontitis in a canine model
DescriptionInflammatory periodontal disease (periodontitis) is widespread in dogs. This study aimed to evaluate site-specific changes in the canine gingival crevicular fluid (GCF) proteome during the longitudinal progression from very mild gingivitis to mild periodontitis. Periodontitis diagnosis in dogs requires anaesthesia, our ultimate aim was to develop a periodontitis diagnostic that could be applied to samples taken from conscious dogs. The objective of this work was to identify potential biomarkers of periodontal disease progression in the GCF of dogs.
HostingRepositoryPRIDE
AnnounceDate2016-03-21
AnnouncementXMLSubmission_2016-03-21_02:56:54.xml
DigitalObjectIdentifier
ReviewLevelPeer-reviewed dataset
DatasetOriginOriginal dataset
RepositorySupportUnsupported dataset by repository
PrimarySubmitterMelissa Grant
SpeciesList scientific name: Canis familiaris (Dog) (Canis lupus familiaris); NCBI TaxID: 9615;
ModificationListiTRAQ4plex-116 reporter+balance reagent acylated residue
InstrumentLTQ Orbitrap Velos
Dataset History
RevisionDatetimeStatusChangeLog Entry
02015-12-14 05:30:51ID requested
12016-03-21 02:56:55announced
Publication List
Davis IJ, Jones AW, Creese AJ, Staunton R, Atwal J, Chapple IL, Harris S, Grant MM, Longitudinal quantification of the gingival crevicular fluid proteome during progression from gingivitis to periodontitis in a canine model. J Clin Periodontol, 43(7):584-94(2016) [pubmed]
Keyword List
curator keyword: Biomedical
submitter keyword: canine, periodontitis, gingivitis, GCF
Contact List
Melissa M Grant
contact affiliationPeriodontal Research Group, School of Dentistry, University of Birmingham
contact emailm.m.grant@bham.ac.uk
lab head
Melissa Grant
contact affiliationUniversity of Birmingham
contact emailm.m.grant@bham.ac.uk
dataset submitter
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Dataset FTP location
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