PXD003272

PXD003272 is an original dataset announced via ProteomeXchange.

Title	Growth-phase regulated acetylation in B. subtilis
Description	To uncover potential regulatory roles for acetylation, we analyzed how acetylation patterns and abundances change between logarithmic and stationary phase growth in Bacillus subtilis. Using acetyllysine peptide enrichment followed by label-free mass spectrometry-based proteomics, we identified over 2,300 unique acetylation sites on proteins that function in many essential pathways. By comparing the changes in acetylation with total cell protein abundances, we discover a subset of specific acetylation events that are stoichiometrically regulated under different growth conditions.
HostingRepository	PRIDE
AnnounceDate	2016-07-08
AnnouncementXML	Submission_2016-07-08_06:15:32.xml
DigitalObjectIdentifier
ReviewLevel	Peer-reviewed dataset
DatasetOrigin	Original dataset
RepositorySupport	Unsupported dataset by repository
PrimarySubmitter	T Greco
SpeciesList	scientific name: Bacillus subtilis subsp. subtilis str. 168; NCBI TaxID: 224308;
ModificationList	monohydroxylated residue; acetylated residue
Instrument	LTQ Orbitrap; LTQ Orbitrap Velos

Revision	Datetime	Status	ChangeLog Entry
0	2015-12-03 01:53:45	ID requested
⏵ 1	2016-07-08 06:15:33	announced

Carabetta VJ, Greco TM, Tanner AW, Cristea IM, Dubnau D, Acetylome and Evidence for a Role of MreB Acetylation in Cell Wall Growth. mSystems, 1(3):(2016) [pubmed]

curator keyword: Biological

submitter keyword: Bacillus, acetyllysine, LFQ

Ileana Cristea
contact affiliation	Department of Molecular Biology, Princeton University, USA
contact email	icristea@princeton.edu
lab head
T Greco
contact affiliation	Molecular Biology
contact email	tgreco@princeton.edu
dataset submitter

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PRIDE project URI

• PRIDE
  1. PXD003272
     1. Label: PRIDE project
     2. Name: Growth-phase regulated acetylation in B. subtilis