PXD003271

PXD003271 is an original dataset announced via ProteomeXchange.

Title	Proteomic analysis of clear cell renal cell carcinoma tissue versus matched normal kidney tissue
Description	We analyzed 84 tumor/normal pairs (177 total) using standard shotgun proteomic techniques in order to characterize the molecular landscape of clear cell renal cell carcinoma (ccRCC) and interrogated changes in protein abundance and biological pathways with ccRCC grade. These tissues were distributed across stage 1 (n = 34), 2 (n = 40), 3 (n = 42), and 4 (n = 52), with 9 pairs also including samples from metastasized tumor. These data can be (and were) combined with a previously published transcriptomic data set from the same sample cohort (NCBI GEO: GSE53757).
HostingRepository	PRIDE
AnnounceDate	2017-10-24
AnnouncementXML	Submission_2017-10-24_01:05:53.xml
DigitalObjectIdentifier	https://dx.doi.org/10.6019/PXD003271
ReviewLevel	Peer-reviewed dataset
DatasetOrigin	Original dataset
RepositorySupport	Supported dataset by repository
PrimarySubmitter	Benjamin Neely
SpeciesList	scientific name: Homo sapiens (Human); NCBI TaxID: 9606;
ModificationList	Deamidated; Oxidation; Acetyl; Carbamidomethyl
Instrument	LTQ

Revision	Datetime	Status	ChangeLog Entry
0	2015-12-02 07:10:35	ID requested
1	2016-04-18 12:17:12	announced
2	2016-05-03 01:51:44	announced	Updated publication reference for PubMed record(s): 27128972.
3	2017-06-20 05:43:52	announced	Updated project metadata.
⏵ 4	2017-10-24 01:05:54	announced	Updated project metadata.

Neely BA, Wilkins CE, Marlow LA, Malyarenko D, Kim Y, Ignatchenko A, Sasinowska H, Sasinowski M, Nyalwidhe JO, Kislinger T, Copland JA, Drake RR, Proteotranscriptomic Analysis Reveals Stage Specific Changes in the Molecular Landscape of Clear-Cell Renal Cell Carcinoma. PLoS One, 11(4):e0154074(2016) [pubmed]

curator keyword: Biomedical

submitter keyword: human, kidney, tissue, LC-MS/MS, ccRCC, renal cell carcinoma

Richard R. Drake
contact affiliation	Department of Cell and Molecular Pharmacology and Experimental Therapeutics, Medical University of South Carolina, Charleston, SC, USA
contact email	draker@musc.edu
lab head
Benjamin Neely
contact affiliation	Medical University of South Carolina
contact email	benaneely@gmail.com
dataset submitter

Dataset FTP location NOTE: Most web browsers have now discontinued native support for FTP access within the browser window. But you can usually install another FTP app (we recommend FileZilla) and configure your browser to launch the external application when you click on this FTP link. Or otherwise, launch an app that supports FTP (like FileZilla) and use this address: ftp://ftp.pride.ebi.ac.uk/pride/data/archive/2016/04/PXD003271

PRIDE project URI

• PRIDE
  1. PXD003271
     1. Label: PRIDE project
     2. Name: Proteomic analysis of clear cell renal cell carcinoma tissue versus matched normal kidney tissue