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PXD003266

PXD003266 is an original dataset announced via ProteomeXchange.

Dataset Summary
Titlemouse liver SWATH-MS - Systems proteomics of liver mitochondria function
DescriptionHere, we have profiled 386 individuals in 80 cohorts of the BXD mouse genetic reference population across two environmental states through a metabolic phenotyping program including glucose response, exercise capacity, and cold response. To understand how the observed phenotypic differences are related to genetic variance, we generated a multilayered set of molecular phenotypes—genomics, transcriptomics, proteomics, and metabolomics across all cohorts, then modeled these molecular patterns with the phenotypic variance.
HostingRepositoryPRIDE
AnnounceDate2024-10-22
AnnouncementXMLSubmission_2024-10-22_04:27:01.881.xml
DigitalObjectIdentifier
ReviewLevelPeer-reviewed dataset
DatasetOriginOriginal dataset
RepositorySupportUnsupported dataset by repository
PrimarySubmitterYibo Wu
SpeciesList scientific name: Mus musculus (Mouse); NCBI TaxID: 10090;
ModificationListmonohydroxylated residue; iodoacetamide derivatized residue
InstrumentTripleTOF 5600
Dataset History
RevisionDatetimeStatusChangeLog Entry
02015-12-02 00:37:53ID requested
12016-06-13 01:07:14announced
22024-10-22 04:27:10announced2024-10-22: Updated project metadata.
Publication List
Williams EG, Wu Y, Jha P, Dubuis S, Blattmann P, Argmann CA, Houten SM, Amariuta T, Wolski W, Zamboni N, Aebersold R, Auwerx J, Systems proteomics of liver mitochondria function. Science, 352(6291):aad0189(2016) [pubmed]
10.1126/science.aad0189;
Keyword List
curator keyword: Biological
submitter keyword: mouse liver, SWATH-MS
Contact List
Ruedi Aebersold
contact affiliationIMSB, ETH Zurich, Switzerland
contact emailaebersold@imsb.biol.ethz.ch
lab head
Yibo Wu
contact affiliationBiology
contact emailwu@imsb.biol.ethz.ch
dataset submitter
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Dataset FTP location
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PRIDE project URI
Repository Record List
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