PXD003224

PXD003224 is an original dataset announced via ProteomeXchange.

Title	Proteomic analysis of sweat samples from tuberculosis patients
Description	We performed a global proteomic profile of eccrine sweat sampled from patients with active pulmonary TB, other lung diseases (non-TB disease), and healthy controls. A comparison of proteomics results between Active-TB, Non-TB and Healthy Controls was done in search for proteins unique to the active TB-patient cohort as well as proteins unique to those without TB disease. We conclude tthat global proteomic profiling of eccrine sweat collected from TB and non-TB patients is a viable approach for the identification of unique proteins differentially present based on clinical cohort. These proteins may represent unique biomarker profiles that upon further verification and validation could be used to develop a non-sputum based test for diagnosis of active TB.
HostingRepository	PRIDE
AnnounceDate	2016-03-14
AnnouncementXML	Submission_2016-03-14_07:22:23.xml
DigitalObjectIdentifier	https://dx.doi.org/10.6019/PXD003224
ReviewLevel	Peer-reviewed dataset
DatasetOrigin	Original dataset
RepositorySupport	Supported dataset by repository
PrimarySubmitter	Lisa Wolfe
SpeciesList	scientific name: Homo sapiens (Human); NCBI TaxID: 9606;
ModificationList	monohydroxylated residue; iodoacetamide derivatized residue
Instrument	LTQ Orbitrap Velos

Revision	Datetime	Status	ChangeLog Entry
0	2015-11-23 00:06:03	ID requested
⏵ 1	2016-03-14 07:22:25	announced

Adewole OO, Erhabor GE, Adewole TO, Ojo AO, Oshokoya H, Wolfe LM, Prenni JE, Proteomic profiling of eccrine sweat reveals its potential as a diagnostic biofluid for active tuberculosis. Proteomics Clin Appl, 10(5):547-53(2016) [pubmed]

curator keyword: Biomedical

submitter keyword: Eccrine, Sweat, Tuberculosis, TB, Proteomics

Jessica E. Prenni
contact affiliation	Proteomics & Metabolomics Facility, Colorado State University, Fort Collins, CO 80523, USA
contact email	jessica.prenni@colostate.edu
lab head
Lisa Wolfe
contact affiliation	Colorado State University
contact email	lisa.wolfe@colostate.edu
dataset submitter

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PRIDE project URI

• PRIDE
  1. PXD003224
     1. Label: PRIDE project
     2. Name: Proteomic analysis of sweat samples from tuberculosis patients