PXD003039

PXD003039 is an original dataset announced via ProteomeXchange.

Title	Mouse Liver S-Palmitoylation ZDHHC13 LC-MS/MS
Description	Protein S-palmitoylation is a reversible post-translational modification which adding 16-carbon palmitate to specific cysteines and contributes to variable biological functions such as protein trafficking, scaffolding and signaling. ZDHHC13 is one of the members of DHHC-containing palmitoyl-acyltransferase (PAT) family of enzyme. The Zdhhc13 deficient mice show the most severe phenotype with amyloidosis, alopecia, and osteoporosis. Here we used quantitative proteomic approach, combining resin-assisted capture (RAC) method and mass spectrometry-based label free strategy to identify the candidate Zdhhc13 substrates from mouse liver tissue.
HostingRepository	PRIDE
AnnounceDate	2024-10-22
AnnouncementXML	Submission_2024-10-22_04:26:04.769.xml
DigitalObjectIdentifier
ReviewLevel	Peer-reviewed dataset
DatasetOrigin	Original dataset
RepositorySupport	Unsupported dataset by repository
PrimarySubmitter	Yi-Ju Chen
SpeciesList	scientific name: Mus musculus (Mouse); NCBI TaxID: 10090;
ModificationList	N-ethylmaleimide derivatized cysteine; monohydroxylated residue; iodoacetamide derivatized residue
Instrument	Q-Tof Premier; LTQ Orbitrap

Revision	Datetime	Status	ChangeLog Entry
0	2015-10-12 02:59:04	ID requested
1	2017-09-29 09:03:50	announced
⏵ 2	2024-10-22 04:26:05	announced	2024-10-22: Updated project metadata.

Shen LF, Chen YJ, Liu KM, Haddad ANS, Song IW, Roan HY, Chen LY, Yen JJY, Chen YJ, Wu JY, Chen YT, Role of S-Palmitoylation by ZDHHC13 in Mitochondrial function and Metabolism in Liver. Sci Rep, 7(1):2182(2017) [pubmed]

10.1038/s41598-017-02159-4;

curator keyword: Biomedical

submitter keyword: ZDHHC13,Mouse, S-Palmitoylation, Liver, LC-MS/MS

Yi-Ju Chen
contact affiliation	Institute of Chemistry, Academia Sinica, Taiwan
contact email	tp7249@gmail.com
lab head
Yi-Ju Chen
contact affiliation	Academia Sinica
contact email	tp7249@gmail.com
dataset submitter

Dataset FTP location NOTE: Most web browsers have now discontinued native support for FTP access within the browser window. But you can usually install another FTP app (we recommend FileZilla) and configure your browser to launch the external application when you click on this FTP link. Or otherwise, launch an app that supports FTP (like FileZilla) and use this address: ftp://ftp.pride.ebi.ac.uk/pride/data/archive/2017/09/PXD003039

PRIDE project URI

• PRIDE
  1. PXD003039
     1. Label: PRIDE project
     2. Name: Mouse Liver S-Palmitoylation ZDHHC13 LC-MS/MS