PXD003032

PXD003032 is an original dataset announced via ProteomeXchange.

Title	Identification and Quantitative Analysis of Cellular Proteins Affected by Treatment with Withaferin A using a SILAC-based Proteomics Approach
Description	Withaferin A (WA) is a major bioactive compound isolated from the medicinal plant Withania somnifera Dunal, also known as ‘‘Ashwagandha’’. A number of published reports suggest various uses for WA including its function as an anti-inflammatory and anti-angiogenic drug molecule. The effects of WA at the molecular level in a cellular environment are not well understood. Knowledge of the molecular mechanism of action of WA could enhance its therapeutic value and may reveal novel pathways it may modulate.
HostingRepository	PRIDE
AnnounceDate	2015-11-10
AnnouncementXML	Submission_2015-11-10_03:54:26.xml
DigitalObjectIdentifier
ReviewLevel	Peer-reviewed dataset
DatasetOrigin	Original dataset
RepositorySupport	Unsupported dataset by repository
PrimarySubmitter	Umesh Jinwal
SpeciesList	scientific name: Mus musculus (Mouse); NCBI TaxID: 10090;
ModificationList	No PTMs are included in the dataset
Instrument	LTQ Orbitrap Elite

Revision	Datetime	Status	ChangeLog Entry
0	2015-10-12 01:37:56	ID requested
⏵ 1	2015-11-10 03:54:27	announced

Narayan M, Seeley KW, Jinwal UK, Identification and quantitative analysis of cellular proteins affected by treatment with withaferin a using a SILAC-based proteomics approach. J Ethnopharmacol, 175():86-92(2015) [pubmed]

submitter keyword: SILAC, proteomics, mass spectrometry, Withaferin A

Umesh Jinwal
contact affiliation	Department of Pharmaceutical Sciences, College of Pharmacy, Byrd Alzheimer’s Institute, University of South Florida-Health, 4001 E. Fletcher Ave, MDC36, Tampa FL, 33613
contact email	ujinwal@health.usf.edu
lab head
Umesh Jinwal
contact affiliation	Department of Pharmaceutical Sciences, College of Pharmacy,Byrd Alzheimer’s Institute, University of South Florida
contact email	ujinwal@health.usf.edu
dataset submitter

Dataset FTP location NOTE: Most web browsers have now discontinued native support for FTP access within the browser window. But you can usually install another FTP app (we recommend FileZilla) and configure your browser to launch the external application when you click on this FTP link. Or otherwise, launch an app that supports FTP (like FileZilla) and use this address: ftp://ftp.pride.ebi.ac.uk/pride/data/archive/2015/11/PXD003032

PRIDE project URI

• PRIDE
  1. PXD003032
     1. Label: PRIDE project
     2. Name: Identification and Quantitative Analysis of Cellular Proteins Affected by Treatment with Withaferin A using a SILAC-based Proteomics Approach