PXD002918

PXD002918 is an original dataset announced via ProteomeXchange.

Title	Analysis of skeletal muscle from a tailored pig model of Duchenne muscular dystrophy
Description	We recently generated a novel genetically engineered pig model displaying the fundamental biochemical, clinical and pathological hallmarks of human DMD. To get insight into the hierarchy of molecular derangements during progression of muscular dystrophy, we performed a label free proteome analysis of biceps femoris muscle samples from 2-day-old and 3-month-old DMD and WT pigs.
HostingRepository	PRIDE
AnnounceDate	2024-10-22
AnnouncementXML	Submission_2024-10-22_04:26:39.605.xml
DigitalObjectIdentifier
ReviewLevel	Peer-reviewed dataset
DatasetOrigin	Original dataset
RepositorySupport	Unsupported dataset by repository
PrimarySubmitter	Thomas Fröhlich
SpeciesList	scientific name: Sus scrofa domesticus (domestic pig); NCBI TaxID: 9825;
ModificationList	acetylated residue; iodoacetamide derivatized residue
Instrument	LTQ Orbitrap

Revision	Datetime	Status	ChangeLog Entry
0	2015-09-15 03:21:15	ID requested
1	2016-09-27 08:34:39	announced
⏵ 2	2024-10-22 04:26:41	announced	2024-10-22: Updated project metadata.

10.1038/srep33362;

Fr, ö, hlich T, Kemter E, Flenkenthaler F, Klymiuk N, Otte KA, Blutke A, Krause S, Walter MC, Wanke R, Wolf E, Arnold GJ, Progressive muscle proteome changes in a clinically relevant pig model of Duchenne muscular dystrophy. Sci Rep, 6():33362(2016) [pubmed]

curator keyword: Biological

submitter keyword: model organism, DMD,PIG, muscle, LC-MS/MS

Thomas Fröhlich
contact affiliation	Dr. Thomas Fröhlich Laboratory for Functional Genome Analysis Gene Center Munich Ludwig-Maximilians-Universität Munich (LMU) Feodor-Lynen-Str. 25 D-81377 München
contact email	frohlich@lmb.uni-muenchen.de
lab head
Thomas Fröhlich
contact affiliation	Laboratory for Functional Genome Analysis Gene Center Munich Ludwig-Maximilians-Universität Munich (LMU) Feodor-Lynen-Str. 25 81377 Munich Germany
contact email	frohlich@genzentrum.lmu.de
dataset submitter

Dataset FTP location NOTE: Most web browsers have now discontinued native support for FTP access within the browser window. But you can usually install another FTP app (we recommend FileZilla) and configure your browser to launch the external application when you click on this FTP link. Or otherwise, launch an app that supports FTP (like FileZilla) and use this address: ftp://ftp.pride.ebi.ac.uk/pride/data/archive/2016/09/PXD002918

PRIDE project URI

• PRIDE
  1. PXD002918
     1. Label: PRIDE project
     2. Name: Analysis of skeletal muscle from a tailored pig model of Duchenne muscular dystrophy