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PXD002894

PXD002894 is an original dataset announced via ProteomeXchange.

Dataset Summary
TitlePhosphoproteome analysis .
DescriptionThe phosphatase activirty and dephosphorylation site are determined by using the recombinant protein. After treatment, the level of specific phosphorylation site is decreased. Also, the biological importance is evaluated through a serial of experiments including immunoprecipitation, western blotting, etc,. Based on this workflow, it is possible to determine the tyrosine phosphorylation since the sample complexity is reduced. This finding suggested this phosphatase play a key role in phosphoregulation.
HostingRepositoryPRIDE
AnnounceDate2024-10-07
AnnouncementXMLSubmission_2024-10-07_10:02:31.643.xml
DigitalObjectIdentifier
ReviewLevelPeer-reviewed dataset
DatasetOriginOriginal dataset
RepositorySupportUnsupported dataset by repository
PrimarySubmitterMiao-Hsia Lin
SpeciesList scientific name: Homo sapiens (Human); NCBI TaxID: 9606;
ModificationListphosphorylated residue
InstrumentOrbitrap Fusion
Dataset History
RevisionDatetimeStatusChangeLog Entry
02015-09-11 01:13:23ID requested
12024-10-07 10:02:33announced
Publication List
Tien SC, Lee HH, Yang YC, Lin MH, Chen YJ, Chang ZF, The Shp2-induced epithelial disorganization defect is reversed by HDAC6 inhibition independent of Cdc42. Nat Commun, 7():10420(2016) [pubmed]
10.1038/ncomms10420;
Fan SM, Tsai CF, Yen CM, Lin MH, Wang WH, Chan CC, Chen CL, Phua KKL, Pan SH, Plikus MV, Yu SL, Chen YJ, Lin SJ, Inducing hair follicle neogenesis with secreted proteins enriched in embryonic skin. Biomaterials, 167():121-131(2018) [pubmed]
10.1016/j.biomaterials.2018.03.003;
Keyword List
curator keyword: Biomedical
submitter keyword: tyrosine phosphorylation,LC-MS/MS
Contact List
miao-hsia lin
contact affiliationInstitute of Chemistry, Academia Sinica
contact emailmiaohsialin@gmail.com
lab head
Miao-Hsia Lin
contact affiliationDepartment of Microbiology, College of Medicine, National Taiwan Unversity
contact emailmiaohsialin@gmail.com
dataset submitter
Full Dataset Link List
Dataset FTP location
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PRIDE project URI
Repository Record List
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