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PXD002877

PXD002877 is an original dataset announced via ProteomeXchange.

Dataset Summary
TitleTranscriptome and proteome derived networks reveal distinct and complementary gene relationships - additional phosphoproteomics data
DescriptionCo-expression networks and gene regulatory networks (GRNs) are emerging as important tools for predicting the functional roles of individual genes at a system-wide scale. To enable network reconstructions we built a large-scale gene expression atlas comprised of 62,547 mRNAs, 17,862 non-modified proteins, and 6,227 phosphoproteins harboring 31,595 phosphorylation sites quantified across maize development. There was little edge conservation in co-expression and GRNs reconstructed using transcriptome versus proteome data yet networks from either data type were enriched in ontological categories and effective in predicting known regulatory relationships. This integrated gene expression atlas provides a valuable community resource. The networks should facilitate plant biology research and they provide a conceptual framework for future systems biology studies highlighting the importance of studying gene regulation at several levels.
HostingRepositoryMassIVE
AnnounceDate2016-09-12
AnnouncementXMLSubmission_2016-09-12_10:07:42.xml
DigitalObjectIdentifier
ReviewLevelNon peer-reviewed dataset
DatasetOriginOriginal dataset
RepositorySupportUnsupported dataset by repository
PrimarySubmitterzhouxin shen
SpeciesList scientific name: Zea mays; NCBI TaxID: 4577;
ModificationListPhospho
InstrumentLTQ Velos
Dataset History
RevisionDatetimeStatusChangeLog Entry
02015-09-08 10:24:10ID requested
12016-09-12 10:07:43announced
Publication List
Dataset with its publication pending
Keyword List
submitter keyword: gene regulatory network, Maize, phosphoproteomics, proteomics, RNA-seq, co-expression network
Contact List
Steven P. Briggs
lab head
zhouxin shen
contact affiliationUCSD
contact emailz1shen@ucsd.edu
dataset submitter
Full Dataset Link List
MassIVE dataset URI
Dataset FTP location
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