PXD002774

PXD002774 is an original dataset announced via ProteomeXchange.

Title	Proteomic profiling of retinoblastoma by high resolution mass spectrometry
Description	We performed a high throughput comparative proteomics study to identify differentially expressed proteins that could serve as putative targets in retinoblastoma. We used iTRAQ based quantitative proteomics approach and analyzed the samples on orbitrap velos mass spectrometer. We identified and quantified a total of 3733 proteins in retinoblastoma when compared with normal adult retina. In total, we identified 987 proteins that were differentially expressed in retinoblastoma with a fold change of ≥2 of which 392 proteins were upregulated and 595 were downregulated.
HostingRepository	PRIDE
AnnounceDate	2017-10-24
AnnouncementXML	Submission_2017-10-24_03:34:57.xml
DigitalObjectIdentifier
ReviewLevel	Peer-reviewed dataset
DatasetOrigin	Original dataset
RepositorySupport	Unsupported dataset by repository
PrimarySubmitter	Sailaja Elchuri
SpeciesList	scientific name: Homo sapiens (Human); NCBI TaxID: 9606;
ModificationList	monohydroxylated residue; iodoacetamide derivatized residue
Instrument	LTQ Orbitrap Velos

Revision	Datetime	Status	ChangeLog Entry
0	2015-08-21 02:02:21	ID requested
1	2017-01-03 03:25:18	announced
⏵ 2	2017-10-24 03:34:58	announced	Updated project metadata.

Danda R, Ganapathy K, Sathe G, Madugundu AK, Ramachandran S, Krishnan UM, Khetan V, Rishi P, Keshava Prasad TS, Pandey A, Krishnakumar S, Gowda H, Elchuri SV, Proteomic profiling of retinoblastoma by high resolution mass spectrometry. Clin Proteomics, 13():29(2016) [pubmed]

curator keyword: Biomedical

submitter keyword: Retinoblastoma, Retina, iTRAQ, Cancer, Mass spectrometry, Quantitative proteomics

Dr. Sailaja V Elchuri
contact affiliation	Department of Nanotechnology, Vision Research Foundation, Sankara Nethralaya, 18-college Road, Nungambakkam, Chennai 600006 India
contact email	sailaja.elchuri@gmail.com
lab head
Sailaja Elchuri
contact affiliation	Sankara Nethralaya
contact email	sailaja.elchuri@gmail.com
dataset submitter

Dataset FTP location NOTE: Most web browsers have now discontinued native support for FTP access within the browser window. But you can usually install another FTP app (we recommend FileZilla) and configure your browser to launch the external application when you click on this FTP link. Or otherwise, launch an app that supports FTP (like FileZilla) and use this address: ftp://ftp.pride.ebi.ac.uk/pride/data/archive/2016/12/PXD002774

PRIDE project URI

• PRIDE
  1. PXD002774
     1. Label: PRIDE project
     2. Name: Proteomic profiling of retinoblastoma by high resolution mass spectrometry