PXD002769

PXD002769 is an original dataset announced via ProteomeXchange.

Title	How C/EBPa creates an elite cell state for reprogramming to pluripotency
Description	Mouse B cells, upon ectopic expression of the transcription factor C/EBPalpha for 18h, can be reprogrammed to induced pluripotent stem (iPS) cells with extremely high efficiency. To understand the molecular control of this phenomenon we performed a time course proteomic analysis by label-free protein quantification of proteins during B cell reprogramming to iPS cells.
HostingRepository	PRIDE
AnnounceDate	2024-10-22
AnnouncementXML	Submission_2024-10-22_04:25:12.562.xml
DigitalObjectIdentifier
ReviewLevel	Peer-reviewed dataset
DatasetOrigin	Original dataset
RepositorySupport	Unsupported dataset by repository
PrimarySubmitter	Michael Wierer
SpeciesList	scientific name: Mus musculus (Mouse); NCBI TaxID: 10090;
ModificationList	No PTMs are included in the dataset
Instrument	Q Exactive

Revision	Datetime	Status	ChangeLog Entry
0	2015-08-20 06:59:21	ID requested
1	2016-02-24 00:04:49	announced
2	2016-06-06 01:32:54	announced	Updated publication reference for PubMed record(s): 24336202.
⏵ 3	2024-10-22 04:25:20	announced	2024-10-22: Updated project metadata.

Di Stefano B, Sardina JL, van Oevelen C, Collombet S, Kallin EM, Vicent GP, Lu J, Thieffry D, Beato M, Graf T, poises B cells for rapid reprogramming into induced pluripotent stem cells. Nature, 506(7487):235-9(2014) [pubmed]

10.1038/nature12885;

curator keyword: Biological

submitter keyword: MaxLFQ, reprogramming,B cells, iPS, Qexactive, LC-MS/MS

Matthias Mann
contact affiliation	Department of Proteomics and Signal Transduction, Max-Planck Institute of Biochemistry, Am Klopferspitz 18, Martinsried, Germany
contact email	mmann@biochem.mpg.de
lab head
Michael Wierer
contact affiliation	Department of Proteomics and Signal Transduction, Max-Planck Institute of Biochemistry, Martinsried, Germany
contact email	wierer@biochem.mpg.de
dataset submitter

Dataset FTP location NOTE: Most web browsers have now discontinued native support for FTP access within the browser window. But you can usually install another FTP app (we recommend FileZilla) and configure your browser to launch the external application when you click on this FTP link. Or otherwise, launch an app that supports FTP (like FileZilla) and use this address: ftp://ftp.pride.ebi.ac.uk/pride/data/archive/2016/02/PXD002769

PRIDE project URI

• PRIDE
  1. PXD002769
     1. Label: PRIDE project
     2. Name: How C/EBPa creates an elite cell state for reprogramming to pluripotency