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PXD002758

PXD002758 is an original dataset announced via ProteomeXchange.

Dataset Summary
Titlestrawberry leaves lysine acetylation LC-MS/MS
DescriptionProtein lysine acetylation is a reversible and dynamic post-translational modification. It plays an important role in regulating diverse cellular processes including chromatin dynamic, metabolic pathways and transcription in both prokaryotes and eukaryotes. Although studies of lysine acetylome on plants have been reported, the throughput was not high enough, hindering the deep understanding of lysine acetylation in plant physiology and pathology. In this study, taking advantages of anti-acetyllysine-based enrichment and high-sensitive-mass spectrometer, we applied an integrated proteomic approach to comprehensively investigate lysine acetylome in strawberry. In total, we identified 1392 acetylation sites in 684 proteins, representing the largest dataset of acetylome in plant to date. To reveal the functional impacts of lysine acetylation in strawberry, intensive bioinformatic analysis was performed. The results significantly expanded our current understanding of plant acetylome and demonstrated that lysine acetylation is involved in multiple cellular metabolism and cellular processes. More interestingly, nearly 50% of all acetylated proteins identified in this work were localized in chloroplast and the vital role of lysine acetylation in photosynthesis was also revealed. Taken together, this study not only established the most extensive lysine acetylome in plants to date, but also systematically suggests the significant and unique roles of lysine acetylation in plants.
HostingRepositoryPRIDE
AnnounceDate2015-10-14
AnnouncementXMLSubmission_2015-10-14_05:08:24.xml
DigitalObjectIdentifier
ReviewLevelPeer-reviewed dataset
DatasetOriginOriginal dataset
RepositorySupportUnsupported dataset by repository
PrimarySubmitterjun zhu
SpeciesList scientific name: Strawberry leafy fruit phytoplasma; NCBI TaxID: 129249;
ModificationListacetylated residue
InstrumentQ Exactive
Dataset History
RevisionDatetimeStatusChangeLog Entry
02015-08-18 02:42:35ID requested
12015-10-14 05:08:25announced
Publication List
Fang X, Chen W, Zhao Y, Ruan S, Zhang H, Yan C, Jin L, Cao L, Zhu J, Ma H, Cheng Z, Global analysis of lysine acetylation in strawberry leaves. Front Plant Sci, 6():739(2015) [pubmed]
Keyword List
curator keyword: Biological
submitter keyword: strawberry leaves, lysine acetylation, MS
Contact List
Xianping Fang
contact affiliationInstitute of Biology, Hangzhou Academy of Agricultural Sciences
contact emailfxpbio@163.com
lab head
jun zhu
contact affiliationPH.D student
contact emailjun_zhu@ptm-biolab.com
dataset submitter
Full Dataset Link List
Dataset FTP location
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PRIDE project URI
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