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PXD002732

PXD002732 is an original dataset announced via ProteomeXchange.

Dataset Summary
TitleProteomics of thyroid tumours - Proteomics of thyroid tumours provides new insights into their molecular composition and changes associated with malignancy
DescriptionAlthough most thyroid tumours are benign, thyroid cancer represents the most common malignancy of the endocrine system, comprising mainly follicular and papillary thyroid carcinomas (FTC and PTC, respectively). Previous studies have shed some light on the molecular pathogenesis of thyroid cancer but there have not been any comprehensive mass spectrometry-based proteomic studies to reveal protein expression differences between thyroid tumours and the molecular alterations associated with tumour malignancy. We applied a label-free quantitative mass spectrometry analysis to compare normal thyroid tissue with the three most common tumours of the thyroid gland: follicular adenoma, follicular carcinoma and papillary carcinoma.
HostingRepositoryPRIDE
AnnounceDate2024-10-22
AnnouncementXMLSubmission_2024-10-22_04:02:33.186.xml
DigitalObjectIdentifier
ReviewLevelPeer-reviewed dataset
DatasetOriginOriginal dataset
RepositorySupportUnsupported dataset by repository
PrimarySubmitterJuan Martinez-Aguilar
SpeciesList scientific name: Homo sapiens (Human); NCBI TaxID: 9606;
ModificationListiodoacetamide derivatized residue
InstrumentTripleTOF 5600
Dataset History
RevisionDatetimeStatusChangeLog Entry
02015-08-17 01:26:42ID requested
12017-05-03 03:53:25announced
22024-10-22 04:02:41announced2024-10-22: Updated project metadata.
Publication List
10.1038/srep23660;
Mart, í, nez-Aguilar J, Clifton-Bligh R, Molloy MP, Proteomics of thyroid tumours provides new insights into their molecular composition and changes associated with malignancy. Sci Rep, 6():23660(2016) [pubmed]
Keyword List
curator keyword: Biomedical
submitter keyword: SWATH,Thyroid cancer proteomics
Contact List
Mark P. Molloy
contact affiliationAustralian Proteome Analysis Facility, Macquarie University, NSW 2109, Australia
contact emailmark.molloy@mq.edu.au
lab head
Juan Martinez-Aguilar
contact affiliationMQ University
contact emailjuan.martinez-aguilar@students.mq.edu.au
dataset submitter
Full Dataset Link List
Dataset FTP location
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PRIDE project URI
Repository Record List
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