PXD002732

PXD002732 is an original dataset announced via ProteomeXchange.

Dataset Summary

Title	Proteomics of thyroid tumours - Proteomics of thyroid tumours provides new insights into their molecular composition and changes associated with malignancy
Description	Although most thyroid tumours are benign, thyroid cancer represents the most common malignancy of the endocrine system, comprising mainly follicular and papillary thyroid carcinomas (FTC and PTC, respectively). Previous studies have shed some light on the molecular pathogenesis of thyroid cancer but there have not been any comprehensive mass spectrometry-based proteomic studies to reveal protein expression differences between thyroid tumours and the molecular alterations associated with tumour malignancy. We applied a label-free quantitative mass spectrometry analysis to compare normal thyroid tissue with the three most common tumours of the thyroid gland: follicular adenoma, follicular carcinoma and papillary carcinoma.
HostingRepository	PRIDE
AnnounceDate	2024-10-22
AnnouncementXML	Submission_2024-10-22_04:02:33.186.xml
DigitalObjectIdentifier
ReviewLevel	Peer-reviewed dataset
DatasetOrigin	Original dataset
RepositorySupport	Unsupported dataset by repository
PrimarySubmitter	Juan Martinez-Aguilar
SpeciesList	scientific name: Homo sapiens (Human); NCBI TaxID: 9606;
ModificationList	iodoacetamide derivatized residue
Instrument	TripleTOF 5600

Dataset History

Revision	Datetime	Status	ChangeLog Entry
0	2015-08-17 01:26:42	ID requested
1	2017-05-03 03:53:25	announced
⏵ 2	2024-10-22 04:02:41	announced	2024-10-22: Updated project metadata.

Publication List

10.1038/srep23660;
Mart, í, nez-Aguilar J, Clifton-Bligh R, Molloy MP, Proteomics of thyroid tumours provides new insights into their molecular composition and changes associated with malignancy. Sci Rep, 6():23660(2016) [pubmed]

10.1038/srep23660;

Mart, í, nez-Aguilar J, Clifton-Bligh R, Molloy MP, Proteomics of thyroid tumours provides new insights into their molecular composition and changes associated with malignancy. Sci Rep, 6():23660(2016) [pubmed]

Keyword List

curator keyword: Biomedical
submitter keyword: SWATH,Thyroid cancer proteomics

curator keyword: Biomedical

submitter keyword: SWATH,Thyroid cancer proteomics

Contact List

Mark P. Molloy
contact affiliation	Australian Proteome Analysis Facility, Macquarie University, NSW 2109, Australia
contact email	mark.molloy@mq.edu.au
lab head
Juan Martinez-Aguilar
contact affiliation	MQ University
contact email	juan.martinez-aguilar@students.mq.edu.au
dataset submitter

Full Dataset Link List

Dataset FTP location NOTE: Most web browsers have now discontinued native support for FTP access within the browser window. But you can usually install another FTP app (we recommend FileZilla) and configure your browser to launch the external application when you click on this FTP link. Or otherwise, launch an app that supports FTP (like FileZilla) and use this address: ftp://ftp.pride.ebi.ac.uk/pride/data/archive/2017/05/PXD002732
PRIDE project URI

Dataset FTP location
NOTE: Most web browsers have now discontinued native support for FTP access within the browser window. But you can usually install another FTP app (we recommend FileZilla) and configure your browser to launch the external application when you click on this FTP link. Or otherwise, launch an app that supports FTP (like FileZilla) and use this address: ftp://ftp.pride.ebi.ac.uk/pride/data/archive/2017/05/PXD002732

PRIDE project URI

Repository Record List

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