PXD002732 is an
original dataset announced via ProteomeXchange.
Dataset Summary
Title | Proteomics of thyroid tumours - Proteomics of thyroid tumours provides new insights into their molecular composition and changes associated with malignancy |
Description | Although most thyroid tumours are benign, thyroid cancer represents the most common malignancy of the endocrine system, comprising mainly follicular and papillary thyroid carcinomas (FTC and PTC, respectively). Previous studies have shed some light on the molecular pathogenesis of thyroid cancer but there have not been any comprehensive mass spectrometry-based proteomic studies to reveal protein expression differences between thyroid tumours and the molecular alterations associated with tumour malignancy. We applied a label-free quantitative mass spectrometry analysis to compare normal thyroid tissue with the three most common tumours of the thyroid gland: follicular adenoma, follicular carcinoma and papillary carcinoma. |
HostingRepository | PRIDE |
AnnounceDate | 2024-10-22 |
AnnouncementXML | Submission_2024-10-22_04:02:33.186.xml |
DigitalObjectIdentifier | |
ReviewLevel | Peer-reviewed dataset |
DatasetOrigin | Original dataset |
RepositorySupport | Unsupported dataset by repository |
PrimarySubmitter | Juan Martinez-Aguilar |
SpeciesList | scientific name: Homo sapiens (Human); NCBI TaxID: 9606; |
ModificationList | iodoacetamide derivatized residue |
Instrument | TripleTOF 5600 |
Dataset History
Revision | Datetime | Status | ChangeLog Entry |
0 | 2015-08-17 01:26:42 | ID requested | |
1 | 2017-05-03 03:53:25 | announced | |
⏵ 2 | 2024-10-22 04:02:41 | announced | 2024-10-22: Updated project metadata. |
Publication List
10.1038/srep23660; |
Mart, í, nez-Aguilar J, Clifton-Bligh R, Molloy MP, Proteomics of thyroid tumours provides new insights into their molecular composition and changes associated with malignancy. Sci Rep, 6():23660(2016) [pubmed] |
Keyword List
curator keyword: Biomedical |
submitter keyword: SWATH,Thyroid cancer proteomics |
Contact List
Mark P. Molloy |
contact affiliation | Australian Proteome Analysis Facility, Macquarie University, NSW 2109, Australia |
contact email | mark.molloy@mq.edu.au |
lab head | |
Juan Martinez-Aguilar |
contact affiliation | MQ University |
contact email | juan.martinez-aguilar@students.mq.edu.au |
dataset submitter | |
Full Dataset Link List
Dataset FTP location
NOTE: Most web browsers have now discontinued native support for FTP access within the browser window. But you can usually install another FTP app (we recommend FileZilla) and configure your browser to launch the external application when you click on this FTP link. Or otherwise, launch an app that supports FTP (like FileZilla) and use this address: ftp://ftp.pride.ebi.ac.uk/pride/data/archive/2017/05/PXD002732 |
PRIDE project URI |
Repository Record List
[ + ]
[ - ]
- PRIDE
- PXD002732
- Label: PRIDE project
- Name: Proteomics of thyroid tumours - Proteomics of thyroid tumours provides new insights into their molecular composition and changes associated with malignancy