PXD002623

PXD002623 is an original dataset announced via ProteomeXchange.

Title	Comparative shotgun proteomics of aqueous humor for cataract, glaucoma and pseudoexfoliation eye disorders.
Description	The aim of this work was to characterize proteome of aqueous humor from subjects with various eye conditions such as cataract, glaucoma and pseudoexfoliation syndrome by high-resolution chromate-mass-spectrometry. Twenty nine human aqueous humor samples were processed by shotgun proteomics. Data was searched using MaxQuant package. Totally, 263 protein groups were identified. Label-free quantitation reported some differentially expressed proteins in aqueous humor proteome for the aforementioned eye diseases.
HostingRepository	PRIDE
AnnounceDate	2016-05-23
AnnouncementXML	Submission_2016-05-23_01:32:08.xml
DigitalObjectIdentifier
ReviewLevel	Peer-reviewed dataset
DatasetOrigin	Original dataset
RepositorySupport	Unsupported dataset by repository
PrimarySubmitter	Irina Ilina
SpeciesList	scientific name: Homo sapiens (Human); NCBI TaxID: 9606;
ModificationList	monohydroxylated residue; acetylated residue; iodoacetamide derivatized residue
Instrument	Q Exactive

Revision	Datetime	Status	ChangeLog Entry
0	2015-07-29 02:47:14	ID requested
⏵ 1	2016-05-23 01:32:10	announced

Kliuchnikova AA, Samokhina NI, Ilina IY, Karpov DS, Pyatnitskiy MA, Kuznetsova KG, Toropygin IY, Kochergin SA, Alekseev IB, Zgoda VG, Archakov AI, Moshkovskii SA, Human aqueous humor proteome in cataract, glaucoma, and pseudoexfoliation syndrome. Proteomics, 16(13):1938-46(2016) [pubmed]

curator keyword: Biomedical

submitter keyword: Proteomics, mass spectrometry, aqueous humor, eye disease, cataract, glaucoma, pseudoexfoliation syndrome

Sergey Moshkovskii
contact affiliation	Laboratory of Medical Proteomics Department of Personalized Medicine Institute of Biomedical Chemistry Moscow
contact email	smosh@mail.ru
lab head
Irina Ilina
contact affiliation	Institute of Biomedical Chemistry, Russia
contact email	irinailyina@gmail.com
dataset submitter

Dataset FTP location NOTE: Most web browsers have now discontinued native support for FTP access within the browser window. But you can usually install another FTP app (we recommend FileZilla) and configure your browser to launch the external application when you click on this FTP link. Or otherwise, launch an app that supports FTP (like FileZilla) and use this address: ftp://ftp.pride.ebi.ac.uk/pride/data/archive/2016/05/PXD002623

PRIDE project URI

• PRIDE
  1. PXD002623
     1. Label: PRIDE project
     2. Name: Comparative shotgun proteomics of aqueous humor for cataract, glaucoma and pseudoexfoliation eye disorders.