PXD002545

PXD002545 is an original dataset announced via ProteomeXchange.

Title	Phosphoproteomic studies of role of LAR protein tyrosine phosphatase in mouse embryonic fibroblasts
Description	To gain insights into the signalling pathways regulated by Leukocyte common antigen-related protein (LAR), including those that are PDGF-dependent, we have carried out the first systematic analysis of LAR-regulated signal transduction using SILAC-based quantitative proteomic and phosphoproteomic techniques. We have analysed differential phosphorylation between wild-type mouse embryo fibroblasts (MEFs) or MEFS in which the LAR cytoplasmic phosphatase domains had been deleted (LARΔP).
HostingRepository	PRIDE
AnnounceDate	2016-04-15
AnnouncementXML	Submission_2016-04-15_05:05:00.xml
DigitalObjectIdentifier
ReviewLevel	Peer-reviewed dataset
DatasetOrigin	Original dataset
RepositorySupport	Unsupported dataset by repository
PrimarySubmitter	Debbie Cunningham
SpeciesList	scientific name: Mus musculus (Mouse); NCBI TaxID: 10090;
ModificationList	phosphorylated residue
Instrument	LTQ Orbitrap Elite

Revision	Datetime	Status	ChangeLog Entry
0	2015-07-15 08:07:47	ID requested
⏵ 1	2016-04-15 05:05:01	announced

Sarhan AR, Patel TR, Creese AJ, Tomlinson MG, Hellberg C, Heath JK, Hotchin NA, Cunningham DL, Regulation of Platelet Derived Growth Factor Signaling by Leukocyte Common Antigen-related (LAR) Protein Tyrosine Phosphatase: A Quantitative Phosphoproteomics Study. Mol Cell Proteomics, 15(6):1823-36(2016) [pubmed]

curator keyword: Biological

submitter keyword: Mouse, fibroblast, LTQ Orbitrap Elite, phosphoproteomics

Debbie L Cunningham
contact affiliation	School of Biosciences, University of Birmingham, Edgbaston, Birmingham, B15 2TT, UK
contact email	d.cunningham@bham.ac.uk
lab head
Debbie Cunningham
contact affiliation	University of Birmingham
contact email	d.cunningham@bham.ac.uk
dataset submitter

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PRIDE project URI

• PRIDE
  1. PXD002545
     1. Label: PRIDE project
     2. Name: Phosphoproteomic studies of role of LAR protein tyrosine phosphatase in mouse embryonic fibroblasts